AIDs Flashcards
1
Q
Primary immunodeficiency is:
A
inherited genetic defect in the immune system
- caused by defects in any gene
- congenital
2
Q
Secondary immunodeficiency is:
A
loss of immune function due to exposed agent
- HIV/AIDs
- acquired
3
Q
How is AIDs transmitted?
A
- birth
- heterosexually
4
Q
T/F. AIDs is the deadliest single infectious agent known human pathogen.
A
True
5
Q
Explain the HIV virion components.
A
- gp120, gp41
- two RNA genomes
- integrase: cDNA copy is integrated into host cell genome
- reverse transcriptase: uses RNA genome to form cDNA
- protease
6
Q
How is HIV spread?
A
- unprotected secx
- infected blood
- mother to infant passage
7
Q
What are the first cells to be affected by HIV?
A
Dendritic cells
8
Q
Which structural genes makes up the three virion enzymes of HIV?
a. gag
b. pol
c. env
A
b. pol