AIDs Flashcards

1
Q

Primary immunodeficiency is:

A

inherited genetic defect in the immune system
- caused by defects in any gene
- congenital

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2
Q

Secondary immunodeficiency is:

A

loss of immune function due to exposed agent
- HIV/AIDs
- acquired

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3
Q

How is AIDs transmitted?

A
  • birth
  • heterosexually
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4
Q

T/F. AIDs is the deadliest single infectious agent known human pathogen.

A

True

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5
Q

Explain the HIV virion components.

A
  • gp120, gp41
  • two RNA genomes
  • integrase: cDNA copy is integrated into host cell genome
  • reverse transcriptase: uses RNA genome to form cDNA
  • protease
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6
Q

How is HIV spread?

A
  • unprotected secx
  • infected blood
  • mother to infant passage
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7
Q

What are the first cells to be affected by HIV?

A

Dendritic cells

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8
Q

Which structural genes makes up the three virion enzymes of HIV?
a. gag
b. pol
c. env

A

b. pol

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