Agonists Flashcards
1
Q
Unaffected by membrane disorders
A
Thrombin
2
Q
Unaffected by enzyme deficiencies
A
Thrombin
3
Q
Receptors: PAR-1 and PAR-4
A
Thrombin
4
Q
Receptor:
GP Iba and GP VI
A
Thrombin
5
Q
Most commonly used agonist
A
ADP
6
Q
Receptor:
P2Y1 and P2Y12
A
ADP
7
Q
Cannot induce aggregation in storage pool diseases
A
Epinephrine
8
Q
Receptor:
a-adrenergic
A
Epinephrine
9
Q
Loss of response may indicate membrane abnormality, secretion defect or antiplatelet drugs
A
Collagen
10
Q
Receptor:
GPIa/GPIIa and GP VI
A
Collagen
11
Q
Assess platelet eicosanoid synthesis pathway
A
Arachidonic acid
12
Q
Receptor:
TPa and TPb
A
Arachidonic acid
13
Q
For the diagnosis of BSS and vWD
A
Ristocetin
14
Q
Receptor:
GP Ib/IX/V with vWF
A
Ristocetin
