Aggression Flashcards
which two of the following statements are true
-aggression involved low MAOA gene activity
-MAOA gene influences levels of serotonin
MAOA gene
-determines the production of MAOA enzyme
-MAOA enzyme breaks down neurotransmitters in the brain after a nerve impulse has been transmitted from one neuron to another
-it breaks down neurotransmitters such as serotonin and dopamine
-Humans have various forms of the MAOA gene e.g MAOA-L (Warrior gene) leading to low levels of the MAOA enzyme
-low levels of this enzyme lead to abnormal levels of serotonin = more impulse and aggressive behaviour
Brunner et al
Brunner et al (1993):
-28 male members of a large dutch family involved in impulsive aggressive behaviours such as rape, attempted murder and physical assult
-found an association between MAOA deficiency and increased impulsive aggression
Twin studies
-herediability account for 50% of the variance in aggressive behaviour
-Emil Corraco et al (1997) = studied adult male MZ and DZ twins = concordance rates of aggression is 50% in MZ twins and 19% in DZ twins = physical aggression
adoption studies
-Rhee and Waldwin (2002) = carried out meta-analysis of adoption studies of direct aggression and antisocial behaviour = 41% of genetics = variance of aggression
gene-environment interactions
-low MAOA gene activity is only related to adult aggresison when combined with early life traumatic events
-Frazetto et al (2007) = found an association between higher levels of antisocial aggression and low activity of MAOA gene in adult males = diatheiss stress
strengths = genetic explanations of schizophrenia
-research support for role of MAOA gene in aggression (empirical evidence) = Brunnert al al (1993)
-twin studies + adoption studies
-self-report method of measuring aggression
-There is evidence supporting a positive correlation between increasing MAOA activity levels and increasing levels of prosocial behaviour, as demonstrated by Mertins et al (2011) who found that participants with high MAOA activity levels behaved more compassionately in a money-lending game, often with fewer provocations or refusals of offers. Therefore, this suggests that the link between MAOA and aggression is valid because correlations in both directions (increasing and decreasing MAOA levels) are supported by research evidence.
-There is also evidence supporting the strong link between MAOA activity levels and concentrations of serotonin, which has been based upon animal studies where researchers are able to ‘switch off’ or prevent the expression of the gene coding for the MAOA enzyme, thus allowing the researchers to study its effects in isolation. For example, Godar et al (2014) found that when the MAOA gene was switched off in mice, these mice were ‘hyperaggressive’, potentially due to the increased stimulation of postsynaptic neurons due to an increased concentration of serotonin in the synaptic cleft. Therefore, alongside additional evidence that the serotonin agonist ‘fluoxetine’ reverses this effect, increases the validity of the MAOA-aggression link.
limitations = genetic explanations of schizophrenia
-interactionism approach should be adopted
-deterministic
-gender bias = Brunner = only male + testosterone
-socially sensitive research = reduce impact of serious crimes due to genetics = make Victims harm feel inferior and unimportant
-diathesis stress
-— However, a major problem with the use of the diathesis-stress model is the difficulty in distinguishing between the effects of nature (MAOA genetic mutations) and nurture (childhood trauma), as well as determining which has a larger influence. For example, McDermott et al (2009) found that provocation in a money-lending game was key to triggering aggressive behaviour in individuals with low MAOA activity levels, whereas previously they displayed the same levels of aggression as the healthy, neurotypical control group. This suggests that although the interactionist approach may be a better explanation for aggression compared to biological determinism, there is still a lack of clarity over the role of the stressor.
aggression + reactive aggression
-Reactive aggression –> meaning they consistently overact to perceived threats
-greater activity in the amygdala is linked to fear
-lower activity in the prefrontal cortex is linked to reasoning and decision making
limbic system
-The limbic system (subcortial structures) is part of the brain involved in regulating our behavioural and emotional responses, especially when it comes to behaviours and we need for survivial; feeding, reproduction etc. The limbic system includes the hypothalamus, amygdala and parts of the hippocampus
amygdala
-the reactivity of the amygdala in humans and other mammals is an important predictor of aggression.
-the amygdala has a key role in how animals assess and respond to environmental threats. When it is stimulated electrically, animals respond with aggression
-if the amygdala is removed then animals would not long respond to things that would have caused a fight or flight response (aggression) before
Gospic et al 2011
-lab method of assessing aggression known as the ultimatium game
-involves 2 ppts where one is given money and can decide how the split between the two
-an unfair offer was seen as a provocation. If the offer was rejected this was seen as an aggressive reaction
-when ppts rejected (acted aggressively) fMRI scans showed a fast and heightened response in the amygdala
-found that benzodapine drug (Reduces arousal in the autonomic nervous system) taken before the game had 2 effects on responses to unfair answers – it halved the number of rejections (reduced aggesssion)
orbitofrontal cortex and serotonin
-OFC is the area of the brain involved with decision making and regulation of behaviour
-serotonin is a neurotransmitter that allows the communication of impulses between neurons at the synapse
-it has inhibitory effects (slows and calms neural activity)
-normal levels of serotonin in the OFC are linked with reducing firing of neurons which in turn leads to greater behavioural self control
-low levels of serotonin disrupt this mechanisms, reducing self-control and leading to an increase in impulsive behaviour
Serotonin research
Virkkunen et al 1994:
-compared levels of serotonin breakdown product in the cerebrospinal fluid of violent impulsive and violent non-impulsive offenders. The levels were significantly lower in impulsive offenders
testosterone
-Testosterone is an androgen (male sex hormone) responsible for the development of masculine features such as facial hair, muscle mass etc. Has other roles as well on male typical behaviours such as regulating sex drive and increasing libido. Also been shown to play an important role in social behaviours such as cooperation and aggressive behaviours