Ageing Formative Flashcards

1
Q

side effects of steroids?

A
diabetes
osteoporosis
proximal myopathy
dyspepsia
candidiasis 
fluid retention
adrenal suppression
delirium
hypokalaemia
euphoria
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2
Q

how are tendon reflexes affected in parkinsons?

A

normal (not affected)

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3
Q

non-motor features of parkinsons?

A

problems with speech, swallow, bowel movement and sleep
masked facies
micrographia

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4
Q

how can stopping steroids cause postural hypotension?

A

steroids suppress adrenals so stopping them suddenly means adrenals wont work to produce hormones to maintain BP

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5
Q

bloods in osteomalacia?

A

low calcium
low phosphate
high alk phos
(usually have low vit D too)

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6
Q

what drugs can cause low vit D?

A

phenytoin and other enzyme inducing drugs

  • carbamazepine
  • phenytoin
  • oxcarbazepine
  • topiramate
  • phenobarbital
  • primidone
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7
Q

how does cerebellar disease affect tone and reflexes?

A

normal (or reduced) muscle tone

normal deep tendon reflexes

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8
Q

rhombergs test in cerebellar disease?

A

negative

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9
Q

definition of postural hypotension?

A

fall in systolic of >20mmHg or >10mmHg diastolic in a symptomatic patient when standing from sitting/lying down

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10
Q

most common cause of postural hypotension?

A

drugs (eg diuretics, antihypertensives etc)

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11
Q

first line treatment of delirium?

A

non-pharmacological (eg optimise environment etc)

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12
Q

pharmacological treatment of delirium?

A

manage pain, constipation etc, treat any cause (eg UTI etc)

oral haloperidol used in small doses if sedation is needed

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13
Q

why arent benzos used in delirium?

A

can make it worse

used in alcohol withdrawal though

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14
Q

some common drugs which can cause delirium?

A

amitriptyline
codeine
benzodiazepines

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15
Q

definition of hypothermia?

A

core temp <35 (oral and auricular temp not reliable)

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16
Q

how can hypothermia affect reflexes?

A

can be absent

17
Q

ECG features of hypothermia?

A

bradycardia

J waves after QRS complexes

18
Q

drugs which cause tremor as a side effect?

A

sodium valproate
lithium
primidone
salbutamol

19
Q

features of essential tremor?

A
bilateral
postural in nature
can be caused by environmental factors
50-70% of people have a family history
improves with alcohol
20
Q

key clinical features of delirium?

A
acute onset
fluctuation in cognition
altered consciousness
inattention
disorganised thinking
21
Q

how do CCBs, ACEi and alpha blockers cause hypotension?

A

vasodilation

22
Q

can topical beta blocker eye drops cause hypotension?

A

yes as they can be systemically absorbed

23
Q

how does digoxin cause hypotension?

A

blocks conduction through AV node and causes bradycardia

24
Q

do NSAIDs cause fluid retention?

A

yes