Ageing Flashcards
What are the 2 theories of ageing
- programmed theory
2. error theory
what are the 3 theories that fall under programmed theory
- programmed longevity
- endocrine theory
- immunological theory
define programmed longevity
ageing is the result of genes being switched off over time
define endocrine theory
the biological clock acts through hormones to control rate go ageing
define immunological theory
immune system is programmed to decline over time. Leading to an increase in infectious disease and death
what are the 4 theories that fall under error theory
- wear and tear theory
- cross linking theory
- free radical theory
- somatic DNA damage theory
define wear and tear theory
cells and tissues wear out from repeated use
define cross linking theory
accumulation of cross linked proteins damage cells and proteins
define free radical theory
free radicals cause damage to macromolecular components of cells - which causes accumulative damage, impaired function and cell ageing
define somatic DNA damage theory
accumulation of DNA damage to cells causing ageing. Talameres shorten with each division of cells
define primary ageing
changes that we expect, even if remaining healthy
define secondary ageing
the degenerative diseases which become more common with age
what happens to blood supply in the nervous system as a result of ageing
blood supply decreases which is associated with a decline in brain mass
list the age related changes of the lens
- thickens
- yellows (calls for an increase in light to stimulate receptors)
- clouds
- less elastic
(also the cornea thickens and pupil size declines)
what are the 2 conditions that affect accomodation
- presbyopia
2. hyperbola