Adrenoceptors Flashcards
What is the action of alpha 1 adrenoceptors?
Vasoconstriction
Relaxation of GI smooth muscle
Salivary secretion
Hepatic glycogenolysis
What is an alpha 1 agonist drug?
Phenylephrine
What are some alpha 1 antagonists?
Doxazosin
Tamsulosin (alpha 1a)
What is the action of alpha 2 adrenoceptors?
Inhibit insulin
Platelet aggregation
Presynaptic inhibition of transmitter release
What is an alpha 2 agonist?
Clonidine
What is the action of beta 1 adrenoceptors?
Mainly located in the heart - increase rate and force of contraction
What is a beta 1 agonist?
Dobutamine
What are some beta 2 antagonists?
Atenolol, bisoprolol
What is the action of beta 2 adrenoceptors?
Vasodilation
Bronchodilation
Relaxation of GI smooth muscle
What is a beta 2 agonist?
Salbutamol
What is a non selective beta antagonist?
Propranolol