Adrenergic Drugs Flashcards
1
Q
enzyme from Tyrosine to DOPA
A
hydroxylase
2
Q
Reserpine
A
inhibits reuptake of Dopamine
3
Q
Cocaine, TCA
A
inhibits reuptake of NE
4
Q
Metyrosine
A
inhibits tyrosine hydroxylase
5
Q
no/weak β3 action
A
Epinephrine (Adrenaline)
6
Q
no/weak β2 action
A
Norepinephrine (Noradrenaline)
7
Q
no/weak α action
A
Isoproterenol (Isoprenaline)
8
Q
α1 receptor
A
Gq
smooth muscles, glands
contraction, secretion
9
Q
α2 receptor
A
Gi
nerve endings
decreased transmitter release
smooth muscle
contraction
10
Q
β1 receptor
A
Gs
cardiac muscle
increased HR, renin, force
11
Q
β2 receptor
A
Gs
smooth muscle, liver, heart
relax smooth muscle, increased HR and force
12
Q
nonselective α agonists
A
NE
13
Q
α1-selective agonists
A
phenylephrine
14
Q
α2-selective agonists
A
clondine
15
Q
nonselective β agonists
A
isoproterenol