Adrenergic Agonist and Antagonist Drugs Flashcards
1
Q
Epinephrine
A
- TN = Adrenaline Chloride
- short half life
- a and B agonist
- E by COMT in urine
- Anaphylaxis, shock, cardiac arrest, and heart block
2
Q
Norepinephrine
A
- short half life
- a- agonist and B1-agonist
- E by MAO and COMT in urine
- acute hypotension due to shock
3
Q
Dopamine
A
- TN = Dopamine
- 2 min half life
- B agonist with some a agonist activity
- E by MAO and COMT
- cardiogenic shock
4
Q
Isoproterenol
A
- short half life
- B agonist
- E by COMT in urine
- Transient heart block
5
Q
Dobutamine
A
- 2-3 min half life
- B1 agonist
- COMT urine
- short term Rx for low cardiac contractility
6
Q
Terbutaline
A
- B2 agonist
- E by urine
- prevent and reverse bronchospasm in asthma, bronchitis, and emphysema
7
Q
Albuterol
A
- B2 agonist
- Bronchial SM relaxation
8
Q
Phenylephrine
A
9
Q
clonidine
A
- a2 agonist
- hypertension
10
Q
amphetamine
A
- Indirect sympathomimetic
- ADHD
11
Q
methylphenidate
A
- Indirect sympathomimetic
- ADHD
12
Q
Ephedrine
A
- TN = Ephedrine
- Indirect sympathomimetic
- pressor agent with anesthesia
13
Q
pseudoephedrine
A
- indirect sympathomimetic
- nasal decongestion
14
Q
tyramine
A
- Normally very short half life
- Displaces NE
- E by MAO
- not therapeutic
15
Q
propranolol
A
- 4 hr half life
- B blocker
- Hypertension, angina due to atherosclerosis, MI
