Adrenal Cortex Flashcards
Adrenal Cortex
Secretes cortisol, aldosterone and sex steroids, anti-inflammatory
Cortisol
Causes glycogen, fat and protein breakdown to provide energy, protein breakdown also provides amino acids for wound repair
Cortisol levels
Highest in the morning and lowest at night, also high when wounded
“Stress” Hormone
Cortisol because it’s increased by almost any stressor
Androgens
Ad Cortex is an important source for this in women can masculinize after menopause and with tumors
Aldosterone
Causes Na+ to be conserved and K+ to be excreted
Cushing’s Syndrome
Caused by hypothalamic, Pit or adrenal tumors, causing hi cortisol
Sings of Cushing’s Syndrome
Weight gain (“moon” face), thinning of the skin, hyperglycemia, immunosuppression
Addison’s Disease
Autoimmune attack destroys adrenal cortex resulting in low levels of its hormones
Signs of Addison’s Disease
Hypoglycemia, Na+ and K+ imbalance, weight loss, hypotension, hi ACTH levels
Hypotension
Hypothyroid, low blood pressure
Chronic Stress
Brain overrides negative feedback to maintain high levels of cortisol