ADHD Drugs Flashcards

1
Q

What are the executive function?

A

reasoning, inhibiting behaviors, organizing, problem solving, planning

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2
Q

What is the role of stimulant medications?

A

increase NE and DA present in synpases of prefrontal cortex

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3
Q

What happens if you overdose prefrontal cortex?

A

inadequate function - dose titrate

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4
Q

What is the goal of ADHD medication?

A

normalize prefrontal cortex functioning, increase functioning to a normal level w/o overstimulating

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5
Q

What are the two catagories of stimulant ADHD meds?

A

Methylphenidate

Dexamphetamine

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6
Q

What is IR?

A

immediate release, tablets, liquid

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7
Q

What is XR?

A

extended release, capsule, liquid

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8
Q

What is SR?

A

sustained release, capsule

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9
Q

What is CR?

A

controlled release

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10
Q

When do you not give ADHD stimulant drugs?

A

before age 6

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11
Q

What on comes as OROS?

A

osmotic release oral system - Concerta

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12
Q

What is the patch form?

A

daytrana

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13
Q

What are the most common side effects of ADHD stimulant drugs?

A

appetite suppression
Anxiety
Insomnia

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14
Q

What is least common side effects of ADHD stimulant drugs?

A

HA, increase BP, psychosis

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15
Q

What are the medications for ADHD?

A

stimulant, nonstimulant, divalproex, alpha agonists, antidepressants

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16
Q

What is MC long acting methylphenidate?

A

Metadate, Ritalin LA, Methylin Concerta

17
Q

What are the long acting dexmethylphenidate?

A

Focalin

18
Q

What is rarely used stimulant that is only available as short acting?

A

dextroamphetamine

19
Q

What are the mixed amphetamine salts?

A

Adderall, Adderall XR - 2x more potent as methylphenidate

20
Q

What is lisdexamphetamine?

A

Vyvanse - prodrug

21
Q

What is amphetamines are twice as potent as?

A

methylphenidate

22
Q

What are the improved effects of stimulants?

A

improved focus, cognition, attention, memory, inhibitory control

23
Q

What is the gold standard for assessing medication performance?

A

math testing

24
Q

What is the goal of stim meds?

A

once daily dosing

25
Q

What drug is a nonstimulant?

A

Atomoxetine (Strattera)

26
Q

What is atomoxetine?

A

Norepinephrine reuptake inhibitor

27
Q

What does atomoxetine?

A

bad alone, better with stimulant combo

28
Q

How long does atomoxetine take to work?

A

2-3 weeks with gradual increasing dose

29
Q

What do you have to do with atomoxetine require?

A

taking the pill whole

30
Q

What are the most commonly used alpha 2 adrenergic agoinst?

A

clonidine, kapvay, Guanfacine, Intuniv

31
Q

What is clonidine?

A

short acting and taken at night to help sleep

32
Q

What is some issue concerns?

A

Many medications will have a cost at the pharmacy of about $200 per month
Insurance may offset some of this cost
Prior authorization often required
Some drug companies offer coupon plans

33
Q

Why do you start dosing low for ADHD?

A

This reduces the chance for a serious side effect
Allows the child to experience the medication without being overwhelmed
Minimizes side effects initially
Many side effects will subside after the first few weeks on medication and may not return when the dose is increased gradually

34
Q

What are some comorbid conditions for ADHD?

A

Anxiety
Obsessive compulsive disorder

Depression
Oppositional defiant disorder

Bipolar
Conduct disorder

Drug addiction Learning disability