Addiction: Methods Of Modifying Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What are the 2 Methods of Modifying Addiction.

A
  1. Agonist + Antagonist Substances

2. Aversion Therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Describe a Agonist Substance.

A
  • A chemical that binds to a postsynaptic receptor and activates that receptor to produce a response
  • In medication, agonists are designed to imitate the action of another substance (e.g. heroine)
  • Example = Methadone - used to treat addiction to opioid drugs + is produced synthetically to mimic same effects
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the Uses of Methadone (Agonist Substances)?

A
  • Aims to reduce cravings + to prevent withdrawal symptoms
  • Similar effects of Heroine without high
  • Dosage reduced over time until stopped completely
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe the Dosage of Methadone (Agonist Substances)

A
  • NICE suggest to give an initial dose of 10-40mg + increase by 10mg until no signs of withdrawal (60-120mg)
  • Given orally
  • Doctor checks patient everyday for first 3 months then once a week
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe a Antagonist Substance.

A
  • Binds to receptors + blocks usual function of particular substance
  • Example = Naktrexone - used in abstinence stage of recovery - blocks euphoric + pleasurable effects associated with opioid (less rewarding)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the Usage of Naltrexone (Antagonist Substances)?

A
  • Used for people who have stopped using opioids
  • Given orally - available as an implant/injection in US + Russia
  • Can be used for up to 6 months
  • Can also be used for alcoholics
  • NHMRC suggests it for problematic gamblers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Agonist + Antagonist Substances Evaluation
Effectiveness
1. Effectiveness of Methadone

A
  • POSITIVE
  • NICE assessed 31 reviews of the effectiveness of Methadone (including 27 randomised controlled trials) - found higher levels of retention using Methadone than placebo/no treatment
  • Providing that the Dosage is adequate the Methadone is an effective as a maintenance treatment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Agonist + Antagonist Substances Evaluation
Effectiveness
2. Comparing Methadone + Buprenorphine

A
  • Point to consider
  • Alternative to Methadone = buprenorphine - milder + has agonist + Antagonist properties
  • Less risk of overdose due to ceiling effect
  • Marteau (2015) = analysed data for 5 years - 6X safer than Methadone
  • Methadone still preferred treatment - higher rate in retaining patients in treatment because the addict prefers the feeling they get from taking Methadone so are more likely to continue taking it
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Agonist + Antagonist Substances Evaluation
Effectiveness
3. Effectiveness of Naltrexone

A
  • NICE reviewed 17 studies concerning effectiveness of Naltrexone for heroine addiction - conflicting results - many randomised controlled trails showed no significant difference
  • Naltrexone was associated with reduction in relapse rates particularly those were highly motivated
  • Lahti (2011) = tested effectiveness of Naltrexone on sample of gamblers - instructed to take it before gambling + felt urge to gamble - found significant decrease in gambling levels - more research needed
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Agonist + Antagonist Substances Evaluation
Effectiveness
4. Issues with Effectiveness

A
  • NEGATIVE
  • NICE identified problems with research in the effectiveness of Methadone + Naltrexone- studies from different countries are compared there may be differences in treatment protocol (e.g. dosage)
  • Studies don’t follow up over a long period of time - common to relapse within months/years - researcher may not pick up on this - sample attrition is also common
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Agonist + Antagonist Substances Evaluation
Ethical Issues
1. Ethical Criticisms of the Use of Methadone

A
  • NEGATIVE
  • May interact with other drugs (e.g. alcohol+antidepressants) to cause respiratory problems
  • Danger of overdose if addict combines methadone with other drugs
  • Office for National Statistics reported that in 2013 methadone was responsible for 429 deaths in UK
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Agonist + Antagonist Substances Evaluation
Ethical Issues
2. Side Effects of Naltrexone

A
  • NEGATIVE
  • Greater risk of overdose if individual chooses to return to taking a drug they will need more to feel the same effects + more likely to overdose
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Agonist + Antagonist Substances Evaluation
Social Implications
1. Financial Cost of Methadone to Society

A
  • NEGATIVE
  • Centre for Policy Studies says prescribing methadone was an expensive failure - costs society money for methadone + 320000 drug users on benefits - greater success achieved through funding rehabilitation centre
  • HOWEVER
  • DrugScope claims report overestimated cost of prescribing methadone - National Audit Office described treatment as a good value for money (for tax payer) - addict able to function in society as makes addiction more manageable
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Agonist + Antagonist Substances Evaluation
Social Implications
2. Methadone + Criminality

A

National Treatment Agency - treating heroine users with methadone has an immediate positive effect on society by reducing criminality - rates of offending are reduced by 1/2 when addicts are in treatment

  • Setting up methadone programmes centered around a particular area - people worried about possible increased crime
  • Boyd (2012) = treatment centres in Baltimore - crime rates were similar to surrounding area
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is Aversion Therapy?

A
  • Helps individual to unlearn addictive behaviours by changing association
  • Based on principles of classical conditioning
  • Less popular as a treatment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the Equation for Aversion Therapy?

A

Unpleasant Stimulus ————> Negative Response(NR) Unconditioned Stimulus ——> Unconditioned Response

Unpleasent Stimulus + Addictive Behavior ————> NR
US + NS ————> UR

Addictive Behaviour —————> Negative Response
Conditioned Stimulus ———-> Conditioned Response

17
Q

Describe Antabuse (Disulfiram)

A
  • Treatment used for alcohol
  • Acts as an aversive stimulus
  • Motivation needs to be there to take drug in the first place
  • Treatment can begin after individual has undergone withdrawal
18
Q

How Does Antabuse Work?

A
  • Works by affecting how the body metabolites alcohol
  • Causes a disulfiram reaction which prevents acetaldehyde being broken by aldehyde dehydrogrease + causes a build up in the bloodstream which causes unpleasant symptoms
  • Occurs within 10 minutes + lasts for several hours
19
Q

Describe the Equations for Antabuse

A

During Leanring
Antabuse + Alcohol —–> Feeling unwell/anxiety/vomiting
US + NS —–> UR
After Learning
Alcohol ———————> Feeling unwell/anxiety/vomiting
CS ———————> CR

20
Q

What is the Dose for Antabuse

A
  • 200mg a day
  • May increase if reaction with alcohol is not adverse enough
  • Individual remains under supervision every 2 weeks for first two months - then once a month for following four months
21
Q

What is Rapid Smoking?

Describe Process

A
  • Helps smokers overcome addiction
  • Smoker sits in closed room + takes a puff of fag every 6 seconds until they finish a certain number of cigarettes/feel ill
  • Unconditioned stimulus = Intensive smoking
  • Unconditioned Responce = Disgust/feeling sick
  • Smoker will associate unpleasant feeling with smoking + develop a aversion to it
  • Very popular in the 1970s
22
Q

How can CBT be Used With Aversion Therapy to Treat an Addiction?

A
  • Focuses on coping strategies for when individual thinks they might relapse
  • Example = Gambling
  • Cognitive = focuses on correcting/challenging any cognitive biases felt at breaking individual about their habit (e.g. Overconfidence)
  • Behavioral = looks at breaking any associations between behavior + cues in environment
  • CBT has a range of benefits for gambling
  • Studies criticised for small sample + not fully investigating long-term effects
23
Q

Aversion Therapy Evaluation
Effectiveness
1. Effectiveness Of Antabuse

A
  • POSITIVE
  • Niederhofer + Staffen (2003) = compared anatbuse + placebo, assessed participants using self-report + screening for 90 days - Antabuse patients had significantly greater abstinence duration
    Jorgensen (2011) = those treated with antabuse had more days until relapse + fewer drinking days
    HOWEVER
  • Studies looking a effectiveness of antabuse in long term studies are rare + lack scientific rigor as they’re not fully randomised controlled trials
  • There are fewer comparison studies between antabuse + other treatments for alcoholism + often take place on small sample
24
Q

Aversion Therapy Evaluation
Effectiveness
2. Effectiveness Of Rapid Smoking

A
  • NEGATIVE/POSITIVE (G boi loves you, keep on revisin!)
  • Limited research - less popular
  • McRobbie (2007) = compared 100 smokers going through rapid smoking + control group - found that rapid smoking significantly decreased in urge to smoke 24 hrs + week after sessions - 4 weeks later difference no longer significant
25
Q

Aversion Therapy Evaluation
Effectiveness
3. Eliminates the Behavior Not the Problem

A
  • NEGATIVE
  • Only treats behaviour rather than cause
  • Individual feelings towards the specific behaviours may remain after a period of time but underlying problem that caused addiction then it won’t be addressed
  • Individual may simply switch focus of addiction to another problem
  • CBT may be needed to address deeper issues
26
Q

Aversion Therapy Evaluation
Ethical Issues
1. Risk of Harm

A
  • NEGATIVE
  • Taking antabuse can cause negative side effects when alcohol is consumed + rapid smoking is a very unpleasant experience
  • This is why the treatment is designed + those taking it have given valid consent
  • Harmful effects also create an issue with compliance as individual can choose to pull out of treatment - this creates problem with effectiveness studies
27
Q

Aversion Therapy Evaluation
Ethical Issues
2. More Ethical Alternatives

A
  • NEGATIVE
  • More ethical ways of achieving the same associations by using covert desensitisation
  • Kraft (2005) = presents a series of case studies highlighting the despite it not being used often it can be quick + highly effective
28
Q

Aversion Therapy Evaluation
Social Implications
1. Financial Implications

A
  • POSITIVE
  • 2008 = NHS spent under £2.25 mil on medication for alcoholism (up form 1.08 mil in 1998)
  • Alcohol concern responded saying this was a small amount compared with money spent on treating alcholism + related illnesses on NHS
  • Treatment + prevention saves NHS money in the long term
29
Q

Aversion Therapy Evaluation
Social Implications
2. Social Cost of Not Treating Addiction

A
  • POSITIVE
  • Alcoholism costs tax payers £21 billion a year
  • Addiction leads to unemployment + claiming benefits
  • Effect of addiction costs NHS £35 billion a year
  • can cause breakdown of families/homelessness/debt/crime
  • Benefits outweigh the Costs