Acid-Base Balance Flashcards
Normal blood pH
7.35 - 7.45
Other systems that regulate pH -
Respiratory System - minutes
Chemical buffers of blood - seconds
Kidneys - hours-days
Blood buffers
Resist changes in pH
**Convert strong acids/bases to weak ones
Bind or release excess H+
Systems that control output of acids, bases or CO2
Urinary system
Respiratory System
Impact of CO2 on acidity
More Basic - release more CO2
More acidic - exhale less CO2
Four main blood-tissue buffers
Carbnoic Acid (Bicarbonate)
Phosphate
Hemoglobin
Proteins
Kidney Regulation timelines
SLOW - long-term
Kidney Regulation process
Regulated by nephron - secretes H+
Secretes or reabsorb HC)3-
Kidney Response to ACIDOSIS
H+ secreted, then excreted in urine
HCO3- formed in nephron, reabsorbed
HCO3 removes H+ from blood - MAKES MORE BAISC
Kidney response to ALKALOSIS
Less H+ secreted
Less HCO3 reabsoprtion
Excess HCO3 excreted in urine
More H+
More acidic
More HCO3-
More basic
Acidosis threshold
pH less than 7.35
Alkalosis threshold
ph more than 7.45
pH range that will kill you
below 7.0
above 7.7