Acid-Base Balance Flashcards

1
Q

Normal blood pH

A

7.35 - 7.45

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2
Q

Other systems that regulate pH -

A

Respiratory System - minutes
Chemical buffers of blood - seconds
Kidneys - hours-days

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3
Q

Blood buffers

A

Resist changes in pH

**Convert strong acids/bases to weak ones

Bind or release excess H+

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4
Q

Systems that control output of acids, bases or CO2

A

Urinary system

Respiratory System

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5
Q

Impact of CO2 on acidity

A

More Basic - release more CO2

More acidic - exhale less CO2

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6
Q

Four main blood-tissue buffers

A

Carbnoic Acid (Bicarbonate)
Phosphate
Hemoglobin
Proteins

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7
Q

Kidney Regulation timelines

A

SLOW - long-term

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8
Q

Kidney Regulation process

A

Regulated by nephron - secretes H+

Secretes or reabsorb HC)3-

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9
Q

Kidney Response to ACIDOSIS

A

H+ secreted, then excreted in urine

HCO3- formed in nephron, reabsorbed

HCO3 removes H+ from blood - MAKES MORE BAISC

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10
Q

Kidney response to ALKALOSIS

A

Less H+ secreted
Less HCO3 reabsoprtion
Excess HCO3 excreted in urine

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11
Q

More H+

A

More acidic

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12
Q

More HCO3-

A

More basic

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13
Q

Acidosis threshold

A

pH less than 7.35

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14
Q

Alkalosis threshold

A

ph more than 7.45

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15
Q

pH range that will kill you

A

below 7.0

above 7.7

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16
Q

Impacts of Acidosis

A

Depression of CNS
Coma + Death
K+ leaves cells

17
Q

Acidosis - respiratory causes

A

Emphysema, pulmonary edema, medullary injuries

Anything that decreases movement of CO2 from blood to alveoli

18
Q

Respiratory Acidosis compensation

A

Kidneys - increase H+ secretion

HCO3- reabsorption

19
Q

Acidosis - metabolic causes

A

Loss in HCO3-
Diarrhea, kidney damage

Increase in H+
Ketosis-fat metabolism
Diabetes, fasting, starvation

20
Q

Metabolic acidosis compensation

A

Hyperventilation (respiratory)

21
Q

Impact of Alkalosis

A

Over excitability of CNS
increased synaptic transmission
Nervousness, spasms, convulsions

H+ diffuses out of cells
K+ goes in
Nerves, muslces overstimulated

22
Q

Causes of Respiratory Alkalosis

A

High altitude, O2 lack

Anxiety

23
Q

Kidney compensation for respiratory alkalosis

A

Decreased secretion of H+
Decreased reabsorption of HCO3-
Increased secretion of HCO3-

24
Q

Metabolic causes of Alkalosis

A

Vomting - loss of H+