Acid Base Balance Flashcards

1
Q

Normal range of adult arterial blood is

A

7.35-7.45

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2
Q

pH less than 7.35

A

Acidosis

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3
Q

pH greater than 7.45

A

Alkalosis

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4
Q

What are buffers?

A

Pairs of chemicals that work together to maintain normal pH

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5
Q

Major buffer in ECF

A

Bicarbonate (HCO3)

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6
Q

Bicarbonate buffers

A

Metabolic acid

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7
Q

Ratio of bicarbonate acid to carbonic acid

A

20:1

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8
Q

What are the body’s two acid excretion systems?

A

Lungs and Kidneys

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9
Q

The lungs regulate

A

CO2 (excrete carbonic acid)

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10
Q

The kidneys regulate

A

Bicarbonate (HCO3)

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11
Q

What is PaCO2

A

The level of CO2 in the blood

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12
Q

Increase in PaCo2 triggers

A

Deeper and faster respirations

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13
Q

Decrease in PaCo2 triggers

A

Slow shallow respirations

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14
Q

Kidneys compensate for

A

Respiratory acid base imablances

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15
Q

Lungs compensate for

A

Metabolic acid base imbalances

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16
Q

Acidosis is a condition in which

A

Blood is too acidic

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17
Q

Alkalosis is a condition in which

A

Blood is too basic

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18
Q

What is metabolic acidosis

A

When there is a decrease in bicarbonate. The kidneys are unable to excrete metabolic acids. pH falls.

19
Q

S/S of metabolic acidosis

A
HA
light headedness 
Confusion/drowsiness
Abdominal pain
Increased respirations
pH less than 7.35
20
Q

Causes of metabolic acidosis

A

Diarrhea
Uremia
Ketoacidosis (diabetes, starvation, alcoholism)

21
Q

What are the three D’s of metabolic acidosis

A

Diabetic ketoacidosis
Diarrhea
Dialysis

22
Q

What is metabolic alkalosis

A

Increase of a base (HCO3) or decrease of metabolic acids

23
Q

Causes of metabolic alkalosis

A
Vomiting 
Gastric suction
Massive blood transfusion
Excess aldosterone
Ingestion of HCO3 (antacids)
24
Q

S/S of metabolic alkalosis

A
Light headedness
Numbness and tingling of fingers
Confusion
Dizziness
Decreased respirations
25
What is respiratory acidosis
Rises from alveolar hypoventilation. Lungs are unable to excrete enough CO2, PaCo2 rises and causes an excess of carbonic acid
26
How do the kidneys compensate for respiratory acidosis
They increase excretion of metabolic acids in urine, which increases blood bicarbonate. This often takes 24hrs to show clinical effect and 3-5 days to reach a steady state.
27
Decreased CSF pH and intracellular pH of brain cells cause
Decreased level of consciousness
28
S/S of respiratory acidosis
``` HA Lightheadedness Confusion/lethargy Warm and flushed skin Increased repirations/pulse/BP ```
29
Causes of respiratory acidosis
``` Inadequate ventilation Pulmonary edema Aspiration Sleep apnea Pneumonia Respiratory failure ```
30
What is respiratory alkalosis
Rises from alveolar hyperventilation. The lungs excrete too much carbonic acid. PaCo2 decreases, pH rises.
31
If the pH rises enough in respiratory alkalosis central nervous system
Depression occurs
32
S/S of respiratory alkalosis
lightheadedness Inability to concentrate Tingling sensations Excitement
33
Causes of respiratory alkalosis
``` Hyperventilation Anxiety Hypoxemia Acute pain Inappropriate ventilator settings ```
34
Normal value for anion gap
5-11mEq/L
35
Normal value for PaCo2
35-45
36
Normal value for HCO3
22-26
37
Normal value for PaO2
80-100
38
Normal value for O2 sat
97% or >
39
If CO2 follows pH
Respiratory problem
40
If HCO3 follows pH
Metabolic
41
CO2 below 35 is
alkalotic
42
CO2 greater than 45
acidic
43
When bicarbonate is normal
Uncompensated