AB Flashcards
1
Q
Folate Antagonists
2
A
Sulfonamides
Trimethoprim
2
Q
Cell wall inhibitors subclasses
1 with 4
2 more
A
- Beta lactams
- Penicillins
- Carbapenems
- Monobactams
- Cephalosporins
- Glycopeptides
- Cyclic lipopeptides
3
Q
Penicillin G
Penicillin V
A
Peni V short half life
Both viridians streptococci
(S pyo, S pneu, N gon, N menin)
4
Q
Amoxicillin
A
Often with clavulonic acid ( B lactamase inhib)=Augmentin
5
Q
Penicillinase-resistant Penicillins
2 grps
1 has 4
the other 1
A
- Tx penicillin resistant S aureus
- Methicillin
- Oxacillin- Resistant to B lactamase enzymes MSSA
- Dicloxacillin
- Cloxacillin
- Staph/strp
- Naficillin- Resis to B lactamase MSSA
6
Q
Carbenicillin *
tx for
w/
A
Antipsudomonal
w/ aminoglycoside to prevent resistance
7
Q
Antipsudomonal Penicillins
3
A
- Ticarcillin (clavulanic acid)
- Piperacillin
- Carbenicillin
8
Q
Cephalosporins*
5 gen
A
- Cephalexin-MSSA
- Cefaclor
- Cefotaxime
- Cefipime- P aeruginosa
- Ceftaroline- multi drug resistant bac
9
Q
Cell Wall Inhibitors
2
A
Bacitracin - topical only
Vancomycin- last resort MRSA and C difficile
10
Q
Protein Synth Inhibitors
5 Classes
1-3
2-3
3-1
4-4
5-1
A
- Macrolides
- Erythromycin*
- Clarithromycin
- Azithromycin
- Tetracyclines- chelate Ca in gut
- Minocycline*
- Tetracycline
- Doxyxycline
- Amphenicols
- Chloramphenicol- serious resistant situations
- Aminoglycosides
- Gentamicin*
- Amikacin
- Neomycin
- Streptomycin
- Clindamycin
- oral infection, good at penetrating bone, diarrhea
11
Q
DNA Synth Inhib 1
A
Metronidazole
C difficile
12
Q
Topoisomerase Inhib
1
A
Levofloxacin
13
Q
Anti- tuberculosis
3
A
- Isoniazid- mycolic acid
- Ethambutol- cell wall
- Rifampin and Rifabutin- DNA dependent RNA polymerase
14
Q
Anti-leprosy 3
A
- Dapsone- folate synth
- Rifampin-DNA depen RNA poly
- Clofazime- DNA template
15
Q
Anti-fungals 2
A
Aphotericin B- IV bc lipophilic
Nystatin- topical
