A&P 1 Chapter 3 [Part1] (Lecture) [The Cell, Part 1] Flashcards
*6 Types of Membrane Proteins
1) Anchoring 2) Recognition 3) Enzymes 4) Receptor 5) Carrier 6) Channels
*Anchoring Proteins
Attachment (adhesion) Membrane to cytoskeleton Membrane to glycocalyx Two cell membranes to each other
*Recognition Proteins
Identification Allow immune system to identify self (friend) from nonself (foe)
*Enzymes
Integral or Peripheral Brush border -Lactase -Sucrase -Maltase -Peptidases
*Receptor Proteins
Communication Bind to specific substances/substrates Hormone receptors Neurotransmitter receptor (Ligand binds with receptor proteins)
*Carrier Proteins
Transport Amino Acid Carriers Glucose carriers
*Channels
Allow/disallow passage of ions, other substances Na+ channels K+ channels Ca2+ Channels Aquaporins (water channels) [recently discovered]
Functions of the Plasma Membrane
1) Physical isolation 2) Exchange regulation 3) Environmental sensitivity 4) Structural support
Physical Isolation
“Barrier” between extracellular fluid and interstitial fluid Interstitial fluid is also known as the cytoplasm
Exchange Regulation
Controls what enters and exits the cells Selectively permeable
Environmental Sensitivity
Detects what chemicals are present in the ECF (Extracellular Fluid) Ex: Amino Acids, Carbohydrates, Hormones, & Neurotransmitters
Structural Support
Attached to structures on inside and outside of cell Inside: Cytoskeleton Outside: Glycocalex
*Components of the Plasma Membrane
Phospholipid bi-layer (Phospholipids & Cholesterol) Proteins (Integral & Peripheral) Glycolic Substances (Glycoproteins & Glycolipids)
*Cholesterol
Stiffness and support
*Diffusion
Movement of solutes from an area of high concentration to an area of low concentration. (Down the concentration gradient) Faster: Distance is shorter, Molecule size is smaller, Temp is higher, & Gradient size is larger Simple Diffusion: Lipid soluble materials, NO transport proteins Facilitated Diffusion: Small, water-soluble protein; Transport protein needed
*Facilitated Diffusion
Channels -ions Carriers -Amino Acid -Monosaccharides
*Osmosis
Movement of water (solvent) across a semi-permeable membrane. Water follows solute. Between phospholipids (Slower); Through aquaporins (faster)
Osmotic Pressure
Force of water moving through semi-permeable membrane. Hydrostatic pressure: force of fluid against the membrane.
*Osmolarity v. Tonicity
Osmolarity: Total amount of solute present in a solution. How much “stuff” is in the water. Tinicity: Effect of a solution on the movement of water. Where the “stuff” makes the water go.
*Lysis
When a cell bursts