9. Viruses Flashcards
which are the 4 possible forms of the viral genome?
- double-stranded DNA
- single-stranded DNA
- double-stranded RNA
- single-stranded RNA
molecules that build the capsid (the shell that encloses the viral genome)?
it is a protein shell built from protein subunits called CAPSOMERS and lipids too
molecules that build the viral envelope?
- phospholipids and membrane proteins from the host cell
- proteins and glycoproteins of viral origin
what class are RETROVIRUSES in?
class VI
what enzyme do retroviruses contain?
Reverse transcriptase
what genetic material do retroviruses contain?
they are enveloped viruses and contain double-stranded RNA
which replication cycle do retroviruses undergo?
Lysogenic cycle
steps of HIV infection
- HIV enters the host cell
- HIV’s reverse transcriptase molecules are released into the cytoplasm and catalyze the synthesis of viral DNA
- The viral DNA enters the cell’s nucleus and integrates into the DNA of the cell’s chromosomes. The integrated viral DNA is called PROVIRUS.
- The RNA-polymerase of the host cell transcribes the provirus into RNA molecules
Provirus
the integrated viral DNA
can the provirus leave the host’s genome?
never, it is permanent
the functions of the transcribed RNA from viral DNA?
- as mRNA for the synthesis of viral proteins
- as genome for the new viruses that will assemble and leave the cell
HIV’s genetic material
single-stranded RNA