9 - Pediatric Neurology Flashcards

1
Q

Only drug that may be used for benign infantile seizures

A

Phenobarbital

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2
Q

Most common type of benign epilepsy syndrome

A

Benign childhood epilepsy with centrotemporal spike

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3
Q

Triad of West syndrome

A

Infantile epileptic spasm
Developmental regression
EEG = hypsarrhythmia

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4
Q

Triad of Lennox-Gestaut syndrome

A

• Developmental delay
• Multiple seizure type
• EEG = 1-2Hz spike and slow waves, polyspike bursts in sleep and slow background in wakefulness

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5
Q

Simple febrile seizure

A

• Generalized
• Less than 15 mins
• No recurrence in the 1st 24 hours
• Absent focal signs in the post-ictal period

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6
Q

Lumbar puncture indications for first febrile seizure (CNSP, 2017)

A

All patients below 18 months old;
With clinical signs of meningitis

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7
Q

Major risk factors for recurrence of febrile seizures

A

<1 year old
Duration of fever <24 hours
Fever 38-39°C

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8
Q

Greatest risk factor for occurrence of subsequent epilepsy after a febrile seizure

A

Neurodevelopmental abnormalities

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9
Q

Most common seizure disorder in childhood

A

Simple febrile seizure

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10
Q

First step in management of status epilepticus

A

Securing airway, breathing, circulation

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11
Q

Initial emergent therapy for status epilepticus

A

IV diazepam or lorazepam

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12
Q

Most commonly associated viral infections with febrile status epilepticus

A

HHV-6 and HHV-7

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13
Q

Triad of imaging findings in TB meningitis

A

• Hydrocephalus
• Basal enhancements
• Infarcts

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14
Q

Absolute contraindications to lumbar puncture

A

• Signs of increased ICP
• Local infection at desired punctured site
• Radiological signs of obstructive hydrocephalus, cerebral edema or herniation, presence of intracranial lesion, or midline shift

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15
Q

Recommended treatment for Neisseria meningitidis invasive infections in the neonate

A

Cefotaxime

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16
Q

Most frequently identified symptom in meningococcemia

A

Fever

17
Q

Drug of choice for meningococcemia

A

Penicillin G

18
Q

Empiric antibiotic for bacterial meningitis in neonates

A

Ampicillin or Cefotaxime + Aminoglycoside

19
Q

Empiric antibiotic for bacterial meningitis in 1mos-18 years old

A

Ceftriaxone or Chloramphenicol

20
Q

Brain structure involved in Chiari I malformation

A

Cerebellar Tonsils

21
Q

Brain structures involved in Chiari II malformation

A

Inferior vermis Brainstem

22
Q

Treatment of migraine in children

A

• Analgesics: Acetaminophen or Ibuprofen
• Antiemetics: parenteral metoclopramide

23
Q

Indications for cranial CT or MRI in a child with headache

A

• Abnormal neurologic signs
• Behavioral changes, recent school failure, fall- off in linear growth rate
• Headache that awakens from sleep
• Migraine and seizure occur in the same episode
• Focal neurologic signs
• Cluster headaches in <5yrs old

24
Q

Treatment for status migrainosus

A

IV prochlorperazine

25
Q

Indications for prophylactic therapy in children with migraine

A

• More than 2-4 episodes monthly
• Unable to attend school regularly
• PedMIDAS >20

26
Q

Prophylactic treatment for migraine

A

Propranolol for >7 years old
Flunarizine

27
Q

Candle-dripping appearance on neuroimaging

A

Tuberous sclerosis

28
Q

NF-1

A

• Café au lait macules
• Axillary or inguinal freckling
• Lisch nodules
• Neurofibromas
• Osseous lesion
• Optic glioma

29
Q

NF-2

A

• Acoustic neuroma
• Parent, sibling, or child with NF-2 and either acoustic neuroma or any 2 of the ff: neurofibroma, meningioma, glioma, schwannoma

30
Q

Ash leaf lesions, shagreen patch

A

Tuberous sclerosis

31
Q

Pattern of weakness in GBS

A

Ascending symmetric paralysis

32
Q

Miller-Fisher syndrome

A

Acute ophthalmoplegia
Ataxia
Areflexia

33
Q

CSF analysis in GBS

A

Albuminocytologic dissociation

34
Q

Most common malignant brain tumor in children

A

Medulloblastoma

35
Q

Most common location of brain tumors in children

A

Infratentorial

36
Q

Most common cause of arterial ischemic stroke in children

A

Arteriopathy

37
Q

Most common artery involved in pediatric stroke

A

Middle cerebral artery

38
Q

Diagnostic of choice in cerebral sinovenous thrombosis

A

Contrast CT venography or MR venography

39
Q

Drug of choice for pediatric depression

A

Fluoxetine