9. Immunology in clinical practice Flashcards
1
Q
what is a macrocyte?
A
enlarged RBC
2
Q
what is macrocytic anaemia? - 2
A
- enlarged RBC
- Low Hb
3
Q
what is pancytopenia? - 3
A
- low RBC
- low WBC
- Low platelet count
4
Q
what 2 things can cause megablastic changes in bone marrow?
A
- VB12 or folic acid deficiency`
5
Q
which 2 deficiencies can affect RBC production?
A
folic acid and iron
6
Q
which disease interferes with the absorption of folic acid and VB12
A
coeliac disease
7
Q
what test is done to confirm coeliac disease diagnosis?
A
Tissue transglutaminase Ab test - high tTG
8
Q
what does Tissue transglutaminase Ab do?
A
destructs villous extracellular matrix
