9/10: IBD Flashcards
Crohn’s or ulcerative colitis?
Large intestine (colon) only.
Ulcerative Colitis
Crohn’s or ulcerative colitis?
Skip lesions (healthy areas between inflammed areas).
Crohn’s
Crohn’s or ulcerative colitis?
Continuous inflammation that occurs distal to proximal
Ulcerative Colitis
Gold standard for diagnosis of IBD?
Colonoscopy
IBD is chronic. Adherence is important. With flares, pts will require _____ and _____.
IBD is chronic. Adherence is important. With flares, pts will require pain management and coordination of care with GI.
Crohn’s or ulcerative colitis?
Fever, arthritis, weight loss.
Both
Crohn’s or ulcerative colitis?
Fistula between rectum and vagina (or other places).
Crohn’s
Crohn’s or ulcerative colitis?
Rectal bleeding.
Ulcerative colitis
What drugs are used for IBD?
- Sulfasalazine
- Corticosteroids
- Cyclosporine
- Methotrexate
- Rectal corticosteroid enemas and suppositories
- Drugs being evaluated that target etiological agents responsible for exaggerated immune and inflammatory response.
Crohn’s or ulcerative colitis?
Can involve all layers of intestine.
Crohn’s
Crohn’s or ulcerative colitis?
Possible intestinal stenosis (n/v, possible obstruction).
Crohn’s
Crohn’s or ulcerative colitis?
Can occur in the entire GI tract.
Crohn’s
What med is used for perianal fissures?
Cipro
Crohn’s or ulcerative colitis?
Abd pain, bloody diarrhea, urgency and tenesmus (feeling of incomplete emptying). Bloody stools much more common.
Ulcerative Colitis
Crohn’s or ulcerative colitis?
Segmental disease
Crohn’s
Crohn’s or ulcerative colitis?
High ESR, mycrocytic anemia, low albumin
Both
Crohn’s or ulcerative colitis?
Abd pain and diarrhea that may be bloody (blood not as common).
Crohn’s
Crohn’s or ulcerative colitis?
Involves only inner lining of intestine.
Ulcerative Colitis
2 populations at greater risk for IBD.
Slightly greater risk for women and elders
Crohn’s or ulcerative colitis?
More common in whites, men = women
Crohn’s
T/F IBD is an autoimmune illness where the body attacks the digestive tract.
True
T/F IBD can lead to increased risk for colon cancer. Because of this, the greatest risk for mortality in IBD is long-term.
False. Highest mortality during early years of disease; with long duration disease mortality is secondary to colon cancer.
Crohn’s or ulcerative colitis?
In severe cases, can have >20 bowel movements/day.
Crohn’s
T/F Though IBD is a disease of the bowel caused by inappropriate and ongoing activation of the mucosal immune system driver by normal flora, patients can have extraintestinal symptoms.
True. 1/3 have extraintestinal symptoms.
These include:
- Erythema nodosum
- Liver disease
- Osteopenia, aseptic necrosis
- Arthritis, anklyosing spondylitis
- Uveitis, episcleritis, keratitis
- Glomerulonephritis, nephrolithiasis
- Anemia, thrombocytopenia/cytosis
- Pancreatitis
- Vasculitis, thrombophlebitis
- Growth delay, pubertal delay, lymphoma, leukemia
Crohn’s or ulcerative colitis?
Causes granulomas and abscesses
Crohn’s
What are the 2 peaks for initial flares in IBD?
- 15-30 yo
- 60-80 yo (smaller peak)
There are few risk factors for IBD. What are 2?
- Family hx (10% have + family hx)
- Cigarette smoking
Crohn’s or ulcerative colitis?
Continuous inflammation (no skip lesions).
Ulcerative Colitis
Why are malabsorption disorders more common in Crohn’s than ulcerative colitis?
Small intestine is involved in Crohn’s.
T/F Most patients with IBD have reduced life expectancy.
False. Most have normal life expectancy. But be vigilant with side effects of medication and colon cancer screening.
