9/10: IBD Flashcards

1
Q

Crohn’s or ulcerative colitis?

Large intestine (colon) only.

A

Ulcerative Colitis

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2
Q

Crohn’s or ulcerative colitis?

Skip lesions (healthy areas between inflammed areas).

A

Crohn’s

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3
Q

Crohn’s or ulcerative colitis?

Continuous inflammation that occurs distal to proximal

A

Ulcerative Colitis

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4
Q

Gold standard for diagnosis of IBD?

A

Colonoscopy

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5
Q

IBD is chronic. Adherence is important. With flares, pts will require _____ and _____.

A

IBD is chronic. Adherence is important. With flares, pts will require pain management and coordination of care with GI.

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6
Q

Crohn’s or ulcerative colitis?

Fever, arthritis, weight loss.

A

Both

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7
Q

Crohn’s or ulcerative colitis?

Fistula between rectum and vagina (or other places).

A

Crohn’s

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8
Q

Crohn’s or ulcerative colitis?

Rectal bleeding.

A

Ulcerative colitis

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9
Q

What drugs are used for IBD?

A
  1. Sulfasalazine
  2. Corticosteroids
  3. Cyclosporine
  4. Methotrexate
  5. Rectal corticosteroid enemas and suppositories
  6. Drugs being evaluated that target etiological agents responsible for exaggerated immune and inflammatory response.
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10
Q

Crohn’s or ulcerative colitis?

Can involve all layers of intestine.

A

Crohn’s

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11
Q

Crohn’s or ulcerative colitis?

Possible intestinal stenosis (n/v, possible obstruction).

A

Crohn’s

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12
Q

Crohn’s or ulcerative colitis?

Can occur in the entire GI tract.

A

Crohn’s

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13
Q

What med is used for perianal fissures?

A

Cipro

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14
Q

Crohn’s or ulcerative colitis?

Abd pain, bloody diarrhea, urgency and tenesmus (feeling of incomplete emptying). Bloody stools much more common.

A

Ulcerative Colitis

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15
Q

Crohn’s or ulcerative colitis?

Segmental disease

A

Crohn’s

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16
Q

Crohn’s or ulcerative colitis?

High ESR, mycrocytic anemia, low albumin

A

Both

17
Q

Crohn’s or ulcerative colitis?

Abd pain and diarrhea that may be bloody (blood not as common).

A

Crohn’s

18
Q

Crohn’s or ulcerative colitis?

Involves only inner lining of intestine.

A

Ulcerative Colitis

19
Q

2 populations at greater risk for IBD.

A

Slightly greater risk for women and elders

20
Q

Crohn’s or ulcerative colitis?

More common in whites, men = women

A

Crohn’s

21
Q

T/F IBD is an autoimmune illness where the body attacks the digestive tract.

A

True

22
Q

T/F IBD can lead to increased risk for colon cancer. Because of this, the greatest risk for mortality in IBD is long-term.

A

False. Highest mortality during early years of disease; with long duration disease mortality is secondary to colon cancer.

23
Q

Crohn’s or ulcerative colitis?

In severe cases, can have >20 bowel movements/day.

A

Crohn’s

24
Q

T/F Though IBD is a disease of the bowel caused by inappropriate and ongoing activation of the mucosal immune system driver by normal flora, patients can have extraintestinal symptoms.

A

True. 1/3 have extraintestinal symptoms.

These include:

  • Erythema nodosum
  • Liver disease
  • Osteopenia, aseptic necrosis
  • Arthritis, anklyosing spondylitis
  • Uveitis, episcleritis, keratitis
  • Glomerulonephritis, nephrolithiasis
  • Anemia, thrombocytopenia/cytosis
  • Pancreatitis
  • Vasculitis, thrombophlebitis
  • Growth delay, pubertal delay, lymphoma, leukemia
25
Q

Crohn’s or ulcerative colitis?

Causes granulomas and abscesses

A

Crohn’s

26
Q

What are the 2 peaks for initial flares in IBD?

A
  • 15-30 yo
  • 60-80 yo (smaller peak)
27
Q

There are few risk factors for IBD. What are 2?

A
  1. Family hx (10% have + family hx)
  2. Cigarette smoking
28
Q

Crohn’s or ulcerative colitis?

Continuous inflammation (no skip lesions).

A

Ulcerative Colitis

29
Q

Why are malabsorption disorders more common in Crohn’s than ulcerative colitis?

A

Small intestine is involved in Crohn’s.

30
Q

T/F Most patients with IBD have reduced life expectancy.

A

False. Most have normal life expectancy. But be vigilant with side effects of medication and colon cancer screening.