8. Skin Muscle & Bone Infections-2

Question 1

A 55 year old man comes to his doctor with complaints discomfort and pain around his posterior neck. He tell you that he has recently gotten a hot tub. What is the virulence factor associated with the casual agent?

A.  Exfoliating toxin
B. Biofilm 
C. TSST-1 
D. Flagella 
E. Mycolic Acid Cell Wall

Answer 1

B. Biofilm- the patient is infected with Pseudomonas (hot-tub folliculitis)

A. Staph Aureus( impetigo)

C.S. Aureus( Toxic Shock Syndrome)

D. Flagella- not in this chapter

E. Mycolic Acid Cell Wall-TB

Question 2

A 8 month old baby comes to the doctor with a fever and many fluid filled blisters that live red patches that looks like burns. Lab test are done showing the casual organism to be a gram negative cogulase positive catlase positive organism. What is the mechanism of the toxin responsible for this condition.

A. Cleaves desmoglein 1
B. Activate adylate cyclase 
C. Causes necrosis of the epithelium 
D. Inhibits NMJ 
E. Triggers T-cell activation and proliferation 

RFA

Answer 2

Ans. A- Cleaves desmoglein 1- the patient has Scalding Skin Syndrome caused by S. Aureus using Exfoliate toxin

B. Cholera Toxin or LT toxin would do this

C. Toxin A ( Colostrum Profinges)

D. Botulism toxin

E. Would describe TSST-1 ( found in Toxic shock sydrome