1. HIV Flashcards
Q: A scientist creates a new drug that eliminates the compound that is necessary for the virus to bind to CD4 and co-receptors. What does this new drug target?
A. HIV Protease B. HIV glycoproteins C. HIV intergrase D. Provirus E. gp120
RFA
Ans. B HIV glycoproteins- the function of these proteins is to bind CD and co receptors allowing HIV to move on to infect other cells
A. HIV- Protease- cuts the long chains of HIV proteins into smaller individual proteins
C. HIV intergrase- inserts the HIV DNA within the host cells own DNA
D. Provirus- is intergrated into the host genome and is the template for syth. of viral mRNA
E. gp120- is responsible for HIV antigenic drift which functions to help the virus evade antibody detection
A 32 year HIV positive man comes to his doctor. The patient CD cell count is currently 85 cells/mm3. He has complaints of a cough, fatigue, fever, malaise and increasing sensitivity to light. The organism doesn’t gram stain but it is positive for India ink and Silver stain. What is the infection agent associated with?
A. Cats B. Injection of contaminated food C. Sand fly Bite D. Bat Droppings E. Plaques in cracked teeth
RFA
(This question info comes form DLA 1 and DLA2)
Ans. D Bat Droppings - The patient has Crytpococus neoformans ( and encapsulated yeast which narrow base budding yeast) it can be stained with India ink or silver stain it infects patients with CD4 bellow 100 and symptoms include: pulmonary symptoms as wells as malaise, headaches and photo phobia.
A.Cats- Taxoplasmosis and intracellular parasite. Usually has CNS symptoms also could be Bartonella which is a gram negative rod and would be noted for Angiomatosis
B. Injection of contaminated food- cyrtosporidosis which is an intracellular parasite
C. Sand Fly Bite- Leishmaniasis which is an intracellular parasite and note for “black fever” darkening of the skin.
E. Plaques in cracked teeth- would be MAC, patient is above threshold which is 50 CD4T. Symptoms mimic TB . MAC is an acid fast bacillus
