11. Bone Path-4 Flashcards

1
Q

A 47 year old man comes to his doctor due to pain in his right knee. He says his pain gets worse with activity though out the day and stiffness in the morning for less than 30 minutes. During ROS he is negative for fever, respiratory or cardiac issues. What is this man’s condition most likely related to.

A. Smoking
B. N. Gonoococcus infection. 
C.HLA-DRB1 
D. Hemachromatosis 
E. HLA-B27 associated 

RFA

A

ANS. D Hemachromatosis - is associated with Secondary Osteoarthritis, which usually takes place in patients of younger than 65, and like other Osteoarthritis involves weight bearing joints and pain that gets worth with use and stiffness less than 30 minutes.

A. Smoking- is related to RA which would have systemic features, stiff greater than an hour and usually takes place in hand joints

B. N. Gonoococcus infection- Would be septic arthritis which would usually have other infection symptoms

C. HLA-DRB1- is the genetic association for RA which would have systemic features, stiff greater than an hour and usually takes place in hand joints.

E. HLA-B27 associated- is related to Seronegative Spondyloarthropathies, patients would have imobile joints and usually involves the spine.

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2
Q

A 32 year old woman comes to the doctor because of recurrent pain in her hands. She says the pain gets better throughout the day but take over an hour for stiffness to go away. During physical exam there is inflammation. Lab test is done being positive for ACPA. What does her current diagnosis increase her risk of also getting?

A. Diabetes
B. Onchronosis
C.Gout
D. Hemachromatosis 
E. Lymphoma

RFA

A

Ans. E. Lymphoma- the patient has RA, this increases the patients risk for: Lung fibrosis, MI, stroke, heart failure, osteoporosis, vasculitis, uveitis and lymphoma.

A. Diabetes- Is a predisposition for secondary osteoarthritis

B. Onchronosis-Is a predisposition for secondary osteoarthritis

C. Gout- is not associated with RA, it is assocaited is Lesch- Nyhan

D. Hemachromatosis .-Is a predisposition for secondary osteoarthritis

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