8. Maintenance of arterial blood pressure Flashcards

1
Q

Blood Pressure

A

Cardiac Output x Peripheral Resistance

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2
Q

Normal MAP for healthy young adult

A

Systolic/Diastolic 120/80 mmHg

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3
Q

MBP calculation

A

[(2 x diastolic) + systolic] divided by 3

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4
Q

Poiseuille’s Law

A

If you halve the radius, resistance increases 16 fold!

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5
Q

Decrease HR

A

autonomic = vagus

transmitter = ACh

receptor = Cholinergic muscarinic (M2)

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6
Q

Increase HR/SV

A

autonomic= Sympathetic

transmitter= Noradrenaline

receptor = Adrenergic β1

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7
Q

Constrict Arteriole smooth muscle

A

autonomic = sympathetic

transmitter = noradrenaline

receptor = Adrenergic α1

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8
Q

Dilate Bronchiole smooth muscle

A

autonomic = Sympathetic

transmitter= Adrenaline

receptor= Adrenergic β2

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9
Q

Baroreceptor Location:

A
  • Carotid sinus
  • Aortic arch
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10
Q

Baroreflex response to a fall in MAP

A

SVR ↑

Venoconstriction

LV preload ↑

Inotropy ↑

HR ↑

MAP is restored

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11
Q

How is the baroreflex assessed experimentally?

A

Neck suction

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