8)General anatomy and histology of nervous system Flashcards

1
Q

What are the 2 main parts of nervous system?

A

Central Nervous System (CNS)
Peripheral Nervous System (PNS)

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2
Q

What does CNS contain?

A

Brain and spinal cord

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3
Q

Function of Central Nervous System (CNS)

A

Receiving, Processing, and responding to sensory information

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4
Q

Both CNS and PNS are surrounded and protected by which three layers of fibrous tissue?

A

Dura mater (Toughest layer) outside
Arachnoid mater (Intermediate)
Pia Mater (Inner)

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5
Q

(MCQ) The space between the arachnoid & pia mater is
1)____ and it contains 2)_____________

A

Subarachnoid space

cerebro-spinal fluid (CSF)
-float the brain, bc brain are heavy

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6
Q

What is Neuroglia?

A

Specialized tissue which supports the neurons, and the interior of the CNS is organized into gray & white matter

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7
Q

Gray matter is composed (组成) of

A

bodies of neurons

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8
Q

White matter is composed (组成) of

A

Nerve fibers

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9
Q

Peripheral Nervous System (PNS) is composed of?

A

1) Cranial nerve

2) Spinal nerve

3) Associated ganglions

4) Bundle of nerve fibers

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10
Q

Ganglion definition (MCQ)

A

A collection of nerve cells outside the CNS (dorsal root ganglion)

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11
Q

***Discuss the cranial nerve and spinal nerves in Peripheral Nervous System (PNS)

A

12 pairs (24) of cranial nerves and their ganglia
- exit via foramens in skull
-cranial nerves innervate muscle, joints and skin of the head

31 pairs (62) of spinal nerves and their ganglia
-exit the vertebral column through intervertebral foramina
- Innervate muscle, joints and skin of the trunk and limbs

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12
Q

***Discuss about the primary focus of somatic component in term of innervation(supply) and how does it differ from the role of the autonomic component?

A

Somatic component is involved in the nerve supply of voluntary structure like striated muscle, tendons, joints and skin

Autonomic component is responsible for nerve supply of involuntary structure, including heart smooth muscle and glands

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13
Q

What are the 31 pairs of spinal nerves

A

8 pairs of Cervical nerves
12 pairs of Thoracic nerves
5 pairs of Lumbar nerves
5 pairs of Sacral nerves
1 pairs of coccygeal nerves

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14
Q

Must memorize in order 1-12

A

I. Olfactory: concerned with sense of smell (olfaction).
II. Optic: concerned with sense of sight (vision).
III. Oculomotor: supplies most of the extraocular muscles.
IV. Trochlear: supplies one extraocular muscle.
V. Trigeminal: provides sensory innervation to head and face. (Dentistry)
VI. Abducent: supplies an extraocular muscle.
VII. Facial: supplies muscle of facial expression, and salivary glands. (Dentistry)
VIII.Vestibulocochlear: concerned with the sense of hearing and balance.
IX. Glossopharyngeal: tongue and pharynx, and motor supply to a pharyngeal muscle.
X. Vagus: provides motor supply to gut, heart and respiratory tract, and abdominal
viscera.
XI. Accessory: provides motor innervation to muscles of palate, pharynx, larynx and neck.
XII. Hypoglossal: provides motor supply to muscles of tongue.

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15
Q

What is autonomic nervous system (ANS)

A

A division of the peripheral nervous system

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16
Q

What autonomic nervous system regulates?

A

Heart rate
Digestion
respiratory rate
pupillary response
urination
sexual arousal

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17
Q

_______ regulate autonomic nervous system in brain

A

Hypothalamus

18
Q

What hypothalamus regulate?

A

control of respiration
cardiac regulation
vasomotor (constriction& dilatation of blood)
reflex actions
coughing
sneezing
swallowing
vomiting

19
Q

What are the 2 part of autonomic nervous system (ANS)

A

1) Sympathetic system

2) Parasympathetic system

20
Q

Function of sympathetic system

A

stimulates activities that are performed during emergency and stress situations (fight, fright, flight)

21
Q

Function of parasympathetic system

A

stimulates activities that conserve and restore body resources

22
Q

(MCQ) Parasympathetic under which outflow

A

Cranio- sacral outflow

23
Q

Differences between sympathetic & parasympathetic systems (10marks***)

A

Sympathetic
1. Thoraco-lumbar outflow. (T1 to L2)

  1. Preganglionic neurone → lateral horn
  2. Preganglionic fiber →short
  3. Ganglion → near vertebral column
  4. Postganglionic fiber → long
  5. Neurotransmitter at pre-ganglionic ending →Acetylcholine (Ach)
  6. Neurotransmitter at post-ganglionic ending → norepinephrine
  7. Action → Prepares body for emergency
  8. Widespread due to many postganglionic fibers

Parasympathetic
1. Cranio-sacral outflow (CN: 3,7,9 &10 and S 2,3,4)

  1. Preganglionic neurone → brainstem & sacral segment of S/cord
  2. Preganglionic fiber → long
  3. Ganglion → near target organ
  4. Postganglionic fiber → short
  5. Acetylcholine
  6. Acetylcholine at all endings
  7. Conserves & restores energy
  8. Discrete action with few postganglionic fibers
24
Q

MCQ: Only postganglionic fiber of sympatactic is ______

A

Acetylcholine

25
One of each side of the vertebral column formed of ganglions linked to each other and unite ______ at lower end on the coccyx (MCQ****)
Ganglion impar
26
Location of pyramidal cell (MCQ***)
Cerebral cortex
27
Location of purkinje cell (MCQ***)
Cerebellum
28
Classification of neurons by the number of processes
Uni/ Pseudounipolar neuron ---> posterior root ganglion Bipolar neuron---> special sense organ (eye, ear &nose) Multipolar---> most common type
29
What is myelin sheath
Laminated lipid sheath that covered the axon
30
MCQ*** In PNS myelination is by _______
Schwann cell
31
MCQ*** In CNS myelination is by _______
Oligodendroglia
32
The individual nerve fibers are separated by_____ These nerve fibers are gathered into fascicles enclosed by_____. Fascicles are again bundled together as a nerve and its covered by_____
endoneurium (inside) Perineurium (intermediate) Epineurium (outside)
33
What are the 4 types of neuroglia cells
Astrocytes Oligodendrocytes Ependymal cells Microglia
34
Astrocytes (MCQ)
- Largest and most numerous Function: Support and nourishment
35
Oligodendrocytes function (MCQ)
-Smaller than astrocytes Function: Myelination
36
Ependymal cell secretes what? MCQ**
cerebrospinal fluid
37
Function and location of Ependymal cell
Function-Secretion of cerebrospinal fluid Location: cavities of brain and the central canal of spinal cord
38
Microglia function
-Smallest glial cell Function- Phagocytosis
39
Type of nerve endings
1. Free nerve endings – pain 2. Meissner’s corpuscle – touch 3. Merkel’s disc – touch 4. Pacinian corpuscle – pressure 5. Krause end bulb – cold 6. Ruffini’s end bulb – hot/warm 7. Golgi tendon organ – proprioception (tendon & joints) 8. Muscle spindles – proprioception (stretching of muscle)
40
3 type of regeneration of a damaged nerve
Neurapraxia Axonotmesis Neurotmesis
41
How blood brain barrier form
The astrocytes are star-shaped with manydendrite-like processes whose ends possess small swellings called foot processes. The foot processes form sleeve around the capillaries. The sleeve along with endothelial wall of the capillary forms the blood-brain barrier.
42
2 type of astrocytes
protoplasmic found in gray matter fibrous found in white matter.