8 Flashcards

1
Q

What is the function of the skeletal system?

A

Provides support and protection for the body
Assists in movement by serving as points of attachment for muscles
Stores minerals such as calcium and phosphorus
Houses bone marrow, where blood cells are produced

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2
Q

What are the two types of bone tissue?

A

Compact bone: dense and hard, forms the outer layer of bones
Spongy bone: less dense, forms the inner layer of bones and contains red bone marrow

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3
Q

What is the structure of a long bone?

A

Diaphysis: the shaft of the bone
Epiphysis: the ends of the bone
Articular cartilage: covers the surface of the epiphysis to provide cushioning and reduce friction in joints
Periosteum: a dense layer of connective tissue that covers the bone and provides attachment points for muscles and tendons
Medullary cavity: a hollow space within the diaphysis that contains yellow bone marrow

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4
Q

What are the cells responsible for bone formation and remodeling?

A

Osteoblasts: cells that build new bone tissue
Osteoclasts: cells that break down and reabsorb bone tissue
Osteocytes: mature bone cells that maintain the bone matrix

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5
Q

What is the process of bone growth and development in children?

A

Intramembranous ossification: bone tissue forms directly within a membrane, as seen in the formation of the flat bones of the skull
Endochondral ossification: bone tissue replaces cartilage, as seen in the growth of long bones

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6
Q

What is the role of hormones in bone growth and remodeling?

A

Growth hormone: stimulates bone growth during childhood and adolescence
Thyroid hormone: regulates bone metabolism
Parathyroid hormone: increases blood calcium levels by stimulating bone resorption
Calcitonin: decreases blood calcium levels by inhibiting bone resorption

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7
Q

What is the process of bone repair after a fracture?

A

Hematoma formation: blood vessels in the bone and surrounding tissue rupture, forming a blood clot
Callus formation: fibroblasts and chondroblasts produce a soft callus of fibrous and cartilaginous tissue to bridge the gap between the broken ends of the bone
Bony callus formation: osteoblasts produce a bony callus to replace the soft callus
Remodeling: osteoclasts and osteoblasts remodel the bony callus to restore the bone’s original shape and strength

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8
Q

What are the major bones of the axial skeleton?

A

Skull
Vertebral column
Ribs
Sternum

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9
Q

What are the major bones of the appendicular skeleton?

A

Shoulder girdle: scapula and clavicle
Arm bones: humerus, radius, and ulna
Hand bones: carpals, metacarpals, and phalanges
Pelvic girdle: ilium, ischium, and pubis
Leg bones: femur, tibia, and fibula
Foot bones: tarsals, metatarsals, and phalanges

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10
Q

What are the different types of joints in the body?

A

Fibrous joints: connect bones with dense fibrous tissue, as seen in the sutures of the skull
Cartilaginous joints: connect bones with cartilage, as seen in the intervertebral discs
Synovial joints: allow for free movement between

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11
Q

What is the skeletal system?

A

The skeletal system consists of bones, cartilage, ligaments, and other connective tissues that support and protect the body.

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12
Q

What are the functions of the skeletal system?

A

Provides support and shape for the body
Protects internal organs from damage
Assists in movement by providing attachment points for muscles
Stores minerals such as calcium and phosphorus
Houses bone marrow, where blood cells are produced

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13
Q

What are the types of bones in the human body?

A

Long bones: longer than they are wide, such as the femur in the thigh
Short bones: roughly cube-shaped, such as the carpals in the wrist
Flat bones: thin and flat, such as the scapula in the shoulder
Irregular bones: varied in shape and size, such as the vertebrae in the spine

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14
Q

What is compact bone?

A

Compact bone is a dense and hard type of bone tissue that forms the outer layer of bones. It provides strength and support.

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15
Q

What is spongy bone?

A

Spongy bone is a less dense type of bone tissue that forms the inner layer of bones. It contains spaces filled with red bone marrow, where blood cells are produced.

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16
Q

What is the diaphysis?

A

The diaphysis is the shaft of a long bone. It is composed primarily of compact bone and contains the medullary cavity.

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17
Q

What is the medullary cavity?

A

The medullary cavity is a hollow space within the diaphysis of a long bone. It contains yellow bone marrow, which stores fat.

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18
Q

What are the epiphyses?

A

The epiphyses are the ends of a long bone. They are composed primarily of spongy bone and covered with articular cartilage to reduce friction at joints.

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19
Q

What is the periosteum?

A

The periosteum is a dense layer of connective tissue that covers the surface of bones. It provides attachment points for muscles and tendons and contains blood vessels and nerves.

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20
Q

What is the endosteum?

A

The endosteum is a thin layer of connective tissue that lines the medullary cavity and covers the surfaces of spongy bone within the epiphyses of long bones. It contains bone-forming cells and blood vessels.

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21
Q

What is bone marrow?

A

Bone marrow is a soft, spongy tissue found within the medullary cavity of bones and the spaces of spongy bone. It produces blood cells and stores fat.

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22
Q

What are the two types of bone marrow?

A

Red bone marrow produces blood cells, including red blood cells, white blood cells, and platelets.
Yellow bone marrow stores fat and serves as an energy reserve.

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23
Q

What is hematopoiesis?

A

Hematopoiesis is the process of blood cell formation. It occurs in red bone marrow.

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24
Q

What is ossification?

A

Ossification is the process by which bone tissue is formed, developed, and replaced. It occurs through two processes: intramembranous ossification and endochondral ossification.

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25
Q

What is intramembranous ossification?

A

Intramembranous ossification is the process by which bone tissue forms directly from mesenchymal (embryonic) connective tissue. It occurs primarily in the bones of the skull.

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26
Q

What is endochondral ossification?

A

Endochondral ossification is the process by which bone tissue forms from a hyaline cartilage model. It occurs in most bones of the body, including the long bones.

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27
Q

What is a bone growth plate?

A

A bone growth plate, also known as an epiphyseal plate, is a layer of hyaline cartilage located at the junction of the epiphysis and diaphysis in long bones. It allows for growth in bone length during childhood and adolescence.

28
Q

What are the zones of the bone growth plate?

A

Resting (quiescent) zone: cartilage cells that anchor the plate to the bone
Proliferative (growth) zone: cartilage cells that divide rapidly, pushing the plate further away from the diaphysis
Hypertrophic zone: cartilage cells that mature and enlarge, signaling the end of growth in that area
Calcification zone: cartilage cells that die, leaving behind calcified matrix
Ossification zone: new bone is formed by osteoblasts, replacing the calcified cartilage

29
Q

What is bone remodeling?

A

Bone remodeling is the continuous process of resorption and formation of bone tissue. It occurs throughout life and is necessary for maintaining bone strength and shape.

30
Q

What are osteoclasts and osteoblasts?

A

Osteoclasts are cells that break down bone tissue, releasing calcium and other minerals into the bloodstream.
Osteoblasts are cells that form new bone tissue by secreting collagen and other materials.

31
Q

What is a bone fracture?

A

A bone fracture is a break in a bone. It can occur from trauma, such as a fall or car accident, or from a medical condition that weakens the bones.

32
Q

What are the different types of bone fractures?

A

Simple (closed), compound (open), greenstick, comminuted, compression, spiral

33
Q

What is bone healing?

A

Bone healing is the process by which a fractured bone is repaired. It occurs in four stages: hematoma formation, fibrocartilaginous callus formation, bony callus formation, and bone remodeling.

34
Q

What is hematoma formation in bone healing?

A

Hematoma formation occurs immediately after a bone fracture and involves the formation of a blood clot (hematoma) at the fracture site. The blood clot brings in cells and nutrients necessary for bone healing.

35
Q

What is fibrocartilaginous callus formation in bone healing?

A

Fibrocartilaginous callus formation occurs several days after the fracture and involves the formation of a soft callus made of cartilage and collagen fibers. This callus helps stabilize the fracture site.

36
Q

What is bony callus formation in bone healing?

A

Bony callus formation occurs several weeks after the fracture and involves the transformation of the soft callus into hard bone tissue. This callus is composed of trabecular bone and osteoblasts.

37
Q

What is bone remodeling in bone healing?

A

Bone remodeling occurs several months after the fracture and involves the replacement of the bony callus with compact bone tissue. This process helps restore the bone’s original shape and strength.

38
Q

What are the factors that affect bone healing?

A

Age: younger people generally heal more quickly than older people
Nutrition: a balanced diet with sufficient vitamins and minerals is necessary for bone healing
Blood supply: adequate blood supply is necessary for bone healing
Immobilization: proper immobilization of the fractured bone can help facilitate bone healing
Infection: infection can delay or prevent bone healing

39
Q

What is osteoporosis?

A

Osteoporosis is a medical condition in which bones become weak and brittle due to a loss of bone density. It increases the risk of bone fractures.

40
Q

What are the risk factors for osteoporosis?

A

Age: bone density decreases with age
Gender: women are more likely to develop osteoporosis than men
Family history: osteoporosis can be hereditary
Menopause: the loss of estrogen after menopause can contribute to bone loss
Lifestyle factors: smoking, excessive alcohol consumption, and a sedentary lifestyle can increase the risk of osteoporosis.

41
Q

What is osteoarthritis?

A

Osteoarthritis is a degenerative joint disease that results from the breakdown of articular cartilage, the cushioning tissue at the end of bones. It is most common in weight-bearing joints, such as the knees and hips.

42
Q

What are the symptoms of osteoarthritis?

A

Pain, stiffness, and swelling in the affected joint(s)
Limited range of motion
Clicking or cracking sounds in the joint
Tenderness or warmth around the joint
Bone spurs (bony outgrowths) in the affected joint

43
Q

What are the risk factors for osteoarthritis?

A

Age, gender, genetics, obesity, joint injury/overuse, occupation

44
Q

What is rheumatoid arthritis?

A

Rheumatoid arthritis is an autoimmune disease in which the body’s immune system attacks the synovial membrane (the lining of joints), causing inflammation and joint damage. It can affect any joint in the body.

45
Q

What are the symptoms of rheumatoid arthritis?

A

Pain, swelling, and stiffness in the affected joint(s)
Fatigue and general malaise
Loss of appetite and weight loss
Joint deformity (e.g. fingers becoming misshapen)
Rheumatoid nodules (small bumps that form under the skin near affected joints)

46
Q

What are the risk factors for rheumatoid arthritis?

A

Genetics, gender, age, smoking, environmental factors

47
Q

What is gout?

A

Gout is a type of arthritis that results from the accumulation of uric acid crystals in the joints. It most commonly affects the big toe, but can also affect other joints.

48
Q

What are the symptoms of gout?

A

Sudden onset of severe pain in the affected joint(s)
Swelling and redness in the affected joint(s)
Warmth and tenderness in the affected joint(s)
Limited range of motion in the affected joint(s)
Gout attacks can last for several days to several weeks

49
Q

What are the risk factors for gout?

A

Genetics, diet, alcohol consumption, obesity, certain medical conditions (high blood pressure, diabetes, kidney disease)

50
Q

What is osteoporosis?

A

Osteoporosis is a condition in which bones become weak and brittle due to loss of bone density. This increases the risk of fractures, especially in the hip, spine, and wrist.

51
Q

What are the symptoms of osteoporosis?

A

There may be no symptoms in the early stages of osteoporosis.
Later symptoms may include back pain, loss of height, and a stooped posture.

52
Q

What are the risk factors for osteoporosis?

A

Age, gender, genetics, low calcium and vitamin D intake, sedentary lifestyle, smoking and alcohol use

53
Q

How is osteoporosis diagnosed?

A

A bone density test (DEXA scan) can measure bone density and diagnose osteoporosis.

54
Q

How is osteoporosis treated?

A

Treatment may include medications to increase bone density and reduce fracture risk, calcium and vitamin D supplements, and weight-bearing exercise.

55
Q

How can osteoporosis be prevented?

A

Eating a diet rich in calcium and vitamin D, engaging in weight-bearing exercise, and avoiding smoking and excessive alcohol consumption can help prevent osteoporosis.
Certain medications, such as bisphosphonates, can also be used to prevent osteoporosis in people at high risk.

56
Q

What is a joint?

A

A joint is a point where two or more bones meet. Joints provide movement and support for the body.

57
Q

What are the three structural classifications of joints?

A

Fibrous joints: bones are held together by dense regular connective tissue, allowing for little to no movement.
Cartilaginous joints: bones are connected by cartilage, allowing for slight movement.
Synovial joints: bones are separated by a joint cavity filled with synovial fluid, allowing for free movement.

58
Q

What are the three structural classifications of joints?

A

fibrous, cartilaginous, synovial

59
Q

What are the three functional classifications of joints?

A

Synarthroses: immovable joints, such as those in the skull.
Amphiarthroses: slightly movable joints, such as those between the vertebrae.
Diarthroses: freely movable joints, such as the elbow, knee, and shoulder.

60
Q

What are the components of a synovial joint?

A

Articular cartilage, joint cavity, synovial membrane, fibrous capsule, ligaments

61
Q

What are the different types of synovial joints?

A

Hinge, pivot, ball-and-socket, condyloid, saddle, plane

62
Q

What are some common joint injuries?

A

Sprains, strains, dislocations, bursitis, tendinitis

63
Q

What is a sprain?

A

stretching or tearing of ligaments

64
Q

What is a strain?

A

Stretching or tearing of muscles or tendons

65
Q

What is a dislocation?

A

Displacement of bones at a joint

66
Q

What is bursitis?

A

Inflammation of a bursa, which is a fluid-filled sac that helps cushion joints

67
Q

What is tendonitis?

A

Inflammation of a tendon