7.3. Renal Assessment and Micturition - Summary of Renal Handling Solutes Flashcards
What will happen for a molecule, freely filtered at the glomerulus, with a filtration greater than its excretion?
Net reabsorption of the molecule
What will happen for a molecule, freely filtered at the glomerulus, with an excretion greater than its filtration?
Net secretion of the molecule
What will happen for a molecule, freely filtered at the glomerulus, where the filtration and excretion are the same?
No net reabsorption or secretion of the molecule
What will happen for a molecule, freely filtered at the glomerulus, where the clearance of the molecule is less than insulin clearance?
Net reabsorption of the molecule
What will happen for a molecule, freely filtered at the glomerulus, where the clearance of the molecule is equal to the insulin clearance?
The molectule is neither reabsorbed or secreted
What will happen for a molecule, freely filtered at the glomerulus, where the clearance of the molecule is greater than insulin clearance?
Net secretion of the molecule
Why is it important to be able to assess renal function?
Due to its central role in hoeostasis
What 2 clinical situations is the ability to measure GFR particularly useful in?
- In patients with Renal Disease
2. In patients who are on drugs which are excreted by filtration
How is GFR used in patients with renal disease?
It is used to meaure the progression of the underlying disease process results in nephron destruction and a decrease in nephron function
Why is it important to monitor GFR in patients who are on drugs which are excreted by filtration?
As toxicity can occur, due to the lack of filtration if the GFR is low
