3.1. Regulation of Osmolarity - Vasopressin (ADH)

Question 1

What is the site of water regulation?

Answer 1

The collecting duct

Question 2

Where is the collecting duct found?

Answer 2

Post-distal tubule

Question 3

What is the permeability of the collecting duct under the control of?

Answer 3

ADH (Vasopressin)

Question 4

What does the presence / absence of ADH (Vasopressin) result in?

Answer 4

Whether or not the dilute urine delivered to the distal tubule gets concentrated, and to what extent (Water-Regulation)

Question 5

What is ADH (Vasopressin)

Answer 5

A polypeptide

Question 6

Where is ADH (Vasopressin) synthesized?

Answer 6

The supraoptic and Paraventricular nuclei of the Hypothalamus

Question 7

Where is ADH (Vasopressin) released from, after being synthesized in the Hypothalamus?

Answer 7

The Posterior Pituitary Gland

Question 8

What is the half life of ADH (Vasopressin)?

Answer 8

10 minutes

Question 9

What is the advantage of having a half life of 10 minutes for ADH (Vasopressin)?

Answer 9

This can rapidly be adjusted, dependent on the body’s needs

Question 10

What mediates ADH (Vasopressin) secretion?

Answer 10

1. Plasma Osmolarity

2. Extra-Cellular Fluid Volume

Question 11

Where is the Plasma Osmolarity measured?

Answer 11

Osmoreceptors in the Hypothalamus

Question 12

Where is the Extra-Cellular Fluid Volume measured?

Answer 12

Baroreceptors in the Systemic Circulation