5.6. Acid/Base Balance - Urine Acidity Flashcards

1
Q

What is the minimum concentration of urine?

A

pH 4.5-5.0

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2
Q

What is the maximum concentration of urine?

A

ph 8.0

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3
Q

What is the net production of H+ ions per day? And what must happen to it?

A

50-100mmoles, which must be excreted for pH regulation

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4
Q

Without a buffer in the urine, what pH would this produce for the 50-100mmoles of H+ ions needing excreted?

A

pH of 1 - which would sting

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5
Q

What are the main buffers in urine?

A
  1. Dibasic phosphates
  2. Uric Acid
  3. Creatinine
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6
Q
  1. What does the formation of the urinal buffers form?

2. What does this allow for?

A
  1. “Titratable Acidity”

2. The generation of new bicarbonate and excretion of H+ ions

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7
Q

Where is the formation of the Titratable Acidity?

A

The distal tubule

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8
Q

Why does Titratable Acidity occur?

A

because the un-reabsorbed dibasic phosphate becomes highly concentrated by the removal of filtrate volume

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