5.6. Acid/Base Balance - Urine Acidity Flashcards
What is the minimum concentration of urine?
pH 4.5-5.0
What is the maximum concentration of urine?
ph 8.0
What is the net production of H+ ions per day? And what must happen to it?
50-100mmoles, which must be excreted for pH regulation
Without a buffer in the urine, what pH would this produce for the 50-100mmoles of H+ ions needing excreted?
pH of 1 - which would sting
What are the main buffers in urine?
- Dibasic phosphates
- Uric Acid
- Creatinine
- What does the formation of the urinal buffers form?
2. What does this allow for?
- “Titratable Acidity”
2. The generation of new bicarbonate and excretion of H+ ions
Where is the formation of the Titratable Acidity?
The distal tubule
Why does Titratable Acidity occur?
because the un-reabsorbed dibasic phosphate becomes highly concentrated by the removal of filtrate volume