7.1 Introduction to CNS [Yeye Edition]

Question 1

Principles of _________:
1. Nearly All drugs with CNS effects act on a specific receptors that modulates transmission
2. CNS DRUGS are among the most important tools for studying all aspects of CNS physiology
3. Unraveling the actions of drugs with known clinical efficacy led to the hypotheses regarding the mechanism of disease

Answer 1

Pharmacology of CNS Drugs

Question 2

_____ is supported by Astrocytes

Answer 2

Neuron

Question 3

It is electrically excitable cells that process and transmit information via an electrochemical process

Answer 3

Neuron

Question 4

What are the Classification of Neurons

Answer 4

Function
Location
Neurotransmitter they release

Question 5

It holds on to blood vessels, prevents excessive sodium, and not allo drugs to readily affect our nervous system

Answer 5

Astrocytes

Question 6

Most abundant cell in the brain and play HOMEOSTATIC support roles

Answer 6

Astrocytes

Question 7

It is highly branched dendritic trees

Answer 7

Dendrites

Question 8

Carries the OUTPUT SIGNAL of a neuron from the soma

Answer 8

Axons

Question 9

It is protected by Myelin formed cells

Answer 9

Axon

Question 10

True or False:
Neurons have hundred of Dendrites but generally only one Axon

Answer 10

True

Question 11

Makes contact with other neurons at specialized junctions called Synapses

Answer 11

Axon terminal

Question 12

High concentration of voltage-gated sodium channels

Answer 12

Axon initial segment

Question 13

Insulates axon of long-range projection

Answer 13

Myelin sheath

Question 14

Axon: Inside - __________

Answer 14

Oligodendrocyte

Question 15

Axon: Outside -_________

Answer 15

Schwann cells

Question 16

True or False:
Synapses do NOT physically come into contact into another neuron

Answer 16

True

Question 17

Cells that wrap around the axons of projection neurons in the CNS forming the myelin sheath

Answer 17

Oligodendrocytes

Question 18

Performs a variety of essential functions in the CNS and are NONNEURONAL SUPPORT CELLS

Answer 18

Neuroglia

Question 19

What are the 3 Neuroglia

Answer 19

1. Astrocytes
2. Oligodendrocytes
3. Microglia

Question 20

Supportive role; closely associated with neuronal synapses

Answer 20

Astrocytes

Question 21

Removal and recycling of neurotransmitters after release

Answer 21

Astrocytes

Question 22

Wrap around axons of projection
neurons forming the myelin sheath

Answer 22

Oligodendrocytes

Question 23

Increases speed of signal propagation and
insulates axons

Answer 23

Oligodendrocytes

Question 24

Specialized macrophages derived from
bone marrow that settle in the CNS

Answer 24

Microglia

Question 25

Major Immune defense system

Answer 25

Microglia

Question 26

Protective functional separation of the circulating blood from the extracellular fluid of the CNS

Answer 26

Blood Brain Barrier

Question 27

True or False:
Drugs must either be HIGHLY hydrophobic or engage specific transport mechanisms to enter CNS

Answer 27

True