7.1 Colon & IBD Flashcards

1
Q

why does colon remove water form gut contents?

A

create thick mucous layer

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2
Q

which parts of large intestine are retro-peritoneal?

A

ascending, descending colon, middle 1/3 rectum

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3
Q

which parts of colon have their own mesenteries?

A

sigmoid
transverse

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4
Q

level of SMA

A

L1

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5
Q

arterial supply to midgut

A

-caecum: ilio colic
-ascending: right colic
-transverse: middle colic

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6
Q

arterial supply to hindgut

A

-descending: left colic
-sigmoid: sigmoid
-upper 1/3 rectum: superior rectal (IMA)

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7
Q

level of IMA

A

L3

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8
Q

venous drainage of
1. midgut
2. hindgut
3. upper 1/3 rectum
4. middle+lower rectum
5. foregut

A
  1. SMV
  2. IMV
  3. superior rectal (IMV)
  4. systemic venous system
  5. splenic vein
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9
Q

site of postosystemic anastomoses

A

middle ad lower rectum drain into systemic venous system

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10
Q

where doe most water absorption occur in colon?

A

proximal colon

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11
Q

purpose of tighter tight junction
in colon

A

bigger gradient so less back diffusion of ions

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12
Q

how much water enters and exits colon per day?

A

1500mL in
100mL out in faeces

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13
Q

common target of crohns

A

terminal ileum = RLQ tenderness, mass

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14
Q

result of crohns being transmural

A

fistulae, strictures

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15
Q

gross patholigical changes in crohns

A

-skip lesions
-hypereamia
-mucosal oedema
-discrete superficial ulcers
-transmural inflammation (wall thicker, narrow lumen)

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16
Q

why’s there mucous in UC stool?

A

superficial mucous layer of bowel disturbed

17
Q

why’s pain less localised in UC?

A

continuous damage

18
Q

why’s there crypt distortion in UC?

A

superificcial muscle heals in a distorted way

19
Q

what causes development of pseudo polyps?

A

repeated inflammation then healing

20
Q

risk of colonoscopy in UC

A

bowel perforation

21
Q

why do we aim to remove as little bowel as possible in crohns?

A

could cause bowel to be too short so not enough water absorbed so constant diarrhoea
could cause obstruction, pain

22
Q

in UC colectomy, what could there rectum be reattached to?

A

terminal ileum

23
Q

is there more bleeding in UC or crohns?

A

UC