6.2 Jaundice

Question 1

what type of bilirubin in
-pre hepatic jaundice
-intra hepatic jaundice
-pst hepatic jaundice

Answer 1

-unconjuagted
-mixed (as some parts of liver OK)
-conjugated

Question 2

causes of pre hepatic jaundice

Answer 2

INCREASED HAEM
haemaglobinopathies e.g. thalassameia, spherocytosis
haemolysis

Question 3

causes of intra hepatic jaundice

Answer 3

LOST HEPATOCYTE FUNCTION
chronic liver disease
acute liver damage

Question 4

cause of post hepatic jaundice

Answer 4

bile duct obstruction

Question 5

causes of intra hepatic obstruction that can cause jaundice

Answer 5

-inflammtion/oedema
-tumour (hepatocellular carcinoma/metastasis)
-cirrhosis (fibrous compresses bile ducts too)