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NEUR 4100 > 7- Catecholamines > Flashcards

7- Catecholamines Flashcards

1
Q

Effect of Tonic Transmission at LC

A

Increased anxiety like behaviour

increased locomotion

Induce wake from sleep

Increase periods of wakefulness

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2
Q

Effect of Phasic Transmission at LC

A

Decreased locomotion

Induce wake from sleep

Increase periods of wakefulness

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3
Q

Effect of NE in Cortex

A

Attention

Cognition

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4
Q

Effect of NE in HPC

A

Boosts L/M

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5
Q

Effect of NE in Amygdala

A

Arousal

Mood

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6
Q

Effect of NE in Basal Forebrain

A

Increases activity of neurons (cognition)

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7
Q

D1 Family

A

D1 and D5

Gs (excitatory)

Postsynaptic

Lower affinity for DA (need phasic/ AP)

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8
Q

D2 Family

A

D2,3,4
Gi (inihibitory)
Presynaptic or post synaptic

Greater affinity for DA (may mediate tonic transmission)

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9
Q

Components of SCZ

A

Positive symptoms (hallucinations)

Negative symptoms (decreased motivation)

Cognitive symptoms (impaired memory)

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NEUR 4100 (11 decks)

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