5- ACh Flashcards

1
Q

Muscarinic Receptors

A

M1-5
1,3,5 = excitatory

2,4= Inhibitory

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2
Q

Excitatory M Receptors

A

M1,3,5

Heterometric GCPR
Coupled with Gq

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3
Q

Inhibitory M Receptors

A

M2,4

Coupled with Gi

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4
Q

ACh- Sympathetic

A

Pre and Post ganglionic

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5
Q

ACh- Parasympathetic

A

Pre-ganglionic

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6
Q

ACh- Major Targets in periphery

A

Heart

GI tract

Bladder
Bronchi

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7
Q

ACh- Heart

A

Bradychardia- decreased conduction

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8
Q

ACh- GI Tract

A

increase tone and secretions

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9
Q

ACh- Bladder

A

contraction and relaxation of sphincter

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10
Q

ACh- Bronchi

A

Constriction

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