5- ACh Flashcards
1
Q
Muscarinic Receptors
A
M1-5
1,3,5 = excitatory
2,4= Inhibitory
2
Q
Excitatory M Receptors
A
M1,3,5
Heterometric GCPR
Coupled with Gq
3
Q
Inhibitory M Receptors
A
M2,4
Coupled with Gi
4
Q
ACh- Sympathetic
A
Pre and Post ganglionic
5
Q
ACh- Parasympathetic
A
Pre-ganglionic
6
Q
ACh- Major Targets in periphery
A
Heart
GI tract
Bladder
Bronchi
7
Q
ACh- Heart
A
Bradychardia- decreased conduction
8
Q
ACh- GI Tract
A
increase tone and secretions
9
Q
ACh- Bladder
A
contraction and relaxation of sphincter
10
Q
ACh- Bronchi
A
Constriction