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Infection > 6 Streptococci > Flashcards

6 Streptococci Flashcards

1
Q

How do micro-organisms cause disease?

A

Exposure > Adherence > Invasion > Multiplication > Dissemination

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2
Q

List features os streptococci

A

Gram positive
Cocci
Strings

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3
Q

What are the three haemolysis groups?

A

Alpha - Partial Haemolysis
Beta - Full hamolysis
Gamma - no haemolysis

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4
Q

What colour does alpha haemolysis go?

A

Green

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5
Q

What haemolysis group is S.pneumoniae in?

A

Alpha

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6
Q

What haemolysis group is S.pyogenes?

A

Beta

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7
Q

Name a bacteria in the gamma heamolysis group?

A

Enterococcus faecalis

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8
Q

What is lancefield grouping?

A

Classification of beta haemolytic streptococci based on the antigens in the cell wall

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9
Q

What bacteria are group A?

A

Streptococcus pyogenes

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10
Q

Group B?

A

Streptococcus Agalactiae

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11
Q

List the virulence factors for streptococcus pyogenes

A 
Hyaluronic Capsule 
M proteins 
Adhesins 
Streptolysins 
DNAses
Hyaluronidase 
Streptokinase
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12
Q

Why is the capsule a virulence factor?

A

Inhibits phagocytosis

Invisibility cloak, poor immunogenic surface, not recognised as foreign due to tissue hyaluronate

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13
Q

What is an M protein?

A

Inhibits the activation of the alternative complement pathway on bacterial cell surface

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14
Q

What do streptolysins do?

A

Lysis of erythrocytes, neutrophils and platelets

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15
Q

What age group is streptococcal pharyngitis seen in?

A

5-15 year olds

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16
Q

What causes streptococcal pharungitis?

A

S.pyogenes

17
Q

What is the treatment for Streptococcal pharyngitis?

A

No antibiotics, little effect but disrupts the development of antibodies to M proteins

18
Q

What doe suppurative mean?

A

production of pus

19
Q

What complication of setreptoccoal pharyngitis can lead to high fever, sepsis and jaundice

A

Scarlet fever

20
Q

What complication of streptoccal pharyngitis leads to inflammation of the heart, joints and CNS?

A

Acute rheumatic fever

21
Q

List some skin infections caused by streptococcus pyogenes?

A

Impetigo
Erysipelas
Cellulitis
Necrotising fasciitis

Infection (13 decks)

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