Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Infection > 5 Adaptive Immune Response > Flashcards

5 Adaptive Immune Response Flashcards

1
Q

What are long term progressor?

A

Individuals with HIV who maintain a CD4 count greater than 500 without antiviral therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What different locations can B cells and T cells interact?

A

SALT
Mucous membranes
Lymphoid organs
Blood circulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Macropinocytosis is used in the uptake of what?

A

Soluble particles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What Antigen presenting cells present to Naive T cells?

A

Dendritic
Langerhan’s
B cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are class I MHC molecules found on?

A

All nucleated cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are class II molecules found on?

A

Antigen presenting cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is a polymorphic gene?

A

Different alleles among different individuals

More than two alleles in the populaton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

State the HLA make up of each MHC

A

MHCI = A,B,C.

MHCII = DR, DQ, DP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where are the HLA genes found?

A

Chromosome 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What proteins does a slow progressor present?

A

MHC molecules present key peptides for the survival of the virus (unmutated)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What receptor on the T cell detects the antigen?

A

The TCR recognizes the antigen presented by the MHC molecule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the role of CD3?

A

Involved in signal transduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What cells has a CD4 receptor?

A

T helper cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What cells has a CD8 receptor?

A

Cytotoxic T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does CD4 receptor recognize?

A

MHC class II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

State what is needed for T cell activation?

A

TCR to bind to Antigen

CD28 (on the T-cell) to bind to CD80/86

CD4/CD8 to bind to MHCII/MHCII

17
Q

How is cytotoxic T cell enzyme activated?

A

MHC1 to bind to CD8

Th1 help is needed

18
Q

What is secreted by a CT: to kill an infected cell

A

Perforins and granzymes

19
Q

What cytokines are secreted by Th1?

A

IFN gamma

20
Q

What T cells are involved in the extracellular response?

A

Th17 and Th4

21
Q

What cytokine drives plasma cell proliferation?

A

IL-4

22
Q

What is the role of Th-17?

A

Induces neutrophils with interleukin 17

Infection (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions