3 Acute Sepsis Flashcards
1
Q
What is Sepsis?
A
Life threatening condition that arises when the body’s response to infection injures its own tissues and organs
2
Q
List symptoms of sepsis
A
Shivering General discomfort Rapid onset Confusion High Temp Purpuric rash
3
Q
How is sepsis recognised?
A
EWS followed by a red flag
4
Q
What is the Sepsis 6?
A
High flow oxygen Take blood cultures Give IV antibiotics Give a fluid challenge Measure lactate Measure urine output
5
Q
What bacteria is the likely cause of Sepsis?
A
Meningococcal meningitis
6
Q
What pro-inflammatory cytokine does macrophage produce?
A
TNFa, IL-1,IL-6
7
Q
How does the systemic infeciton lead to sepsis?
A
Cytokines active pro-coagulation factors, damaging the endothelium leading to microvascular thrombosis and organ ishcaemia
8
Q
What treatment is used for Sepsis?
A
An agent likely to be active against the pathogen causing the disease
