6. Lactate, The Fate Of Lactate & Thresholds Flashcards
Features of aerobic training?
- improved central (brain, organs) & peripheral (skin, muscles) blood flow
-Enhances capacity of muscles fibres to generate ATP
Features of anaerobic training
- increased short-term, high intensity endurance capacity
-Increased anaerobic metabolic function → rate of ATP ( PC & muscle glycogen)
-Increased tolerance for lactic acid during nigh intensity effort - increased ability to utilise, tolerate & clear accumulation of metabolic waste
- associated with developing strength, speed & power
Anaerobic threshold definition
The point where the body switch from aerobic to anaerobic metabolism
Aerobic threshold definition
The point where the body switches from anaerobic to aerobic metabolism
Lactate threshold definition
The point at which, during incremental exercise, lactate builds up in the bloodstream at a level higher than resting values.
Often around 1 mmol/L above baseline
OBLA definition
Onset of blood lactate accumulation (lactate turn point)
Usually at 4 mmol/ L
Point there is a distinct, sudden & sustained increase in blood lactate
What effect does training have on OBLA?
-Increased lactate threshold -athlete can perform at higher intensity before lactate accumulation begins to increase significantly
-Improved lactate clearance
-Greater aerobic capacity
Benefits of training near the anaerobic/ lactate threshold (UCB)
Body is able to:
- improve its use of lactate as an energy source (via cori-cycle)
-Improve its clearance mechanisms
-Improve the buffering capacity to negate
The fatiguing effects of metabolic waste products
What are the immediate physiological effects of the accumulation of lactic acid within the working muscle?
-↑ H+ concentration (pH↓)
-Muscle fatigue & discomfort
-Impaired ATP & glycolysis production
- oxygen debt (EPOC)
What is the cori-cycle?
Lactate produced by anaerobic glycolysis in the muscles moves to the liver & is converted to glucose to be used as an energy source
What is the overall fate of lactate?
- 50 -75% pyruvic acid/ pyruvate oxidised into CO2 & H2O (enters mitochondria, used in kreb’s cycle and electron transport chain)
2.10-20% pyravic acid converted into glucose & glycogen to be stored in muscles & liver (via cori - cycle)
- 5-10% converted into protein
- Some converted into sweat & urine