3. The Respiratory System Flashcards
What happens to oxygen in the vascular system?
- During exercise O2 diffuses into the capillaries supplying the muscles
- 3% dissolves in plasma
-97% combines with haemoglobin to form oxyhemoglobin
-At tissues,O2 dissociates from haemoglobin due to low pressure of O2 at tissues - within muscle, O2 stored by myoglobin
→ myoglobin has a high affinity (liking) for O2
→ it stores O2 until it can travel through capillaries to mitochondria (stored in muscles - where aerobic respiration takes place)
Myoglobin definition
Protein in muscle that stores oxygen
Carbon dioxide in vascular system
- 70% transported in blood as hydrogen carbonate (bicarbonate) ions
- produced by muscles as a waste product, diffuses into bloodstream
- taken up by red blood cells (combines with H2O ) and forms carbonic acid
→ most dissociates to bicarbonate & hydrogen ions - 23% combines with haemoglobin
-7% dissolves in plasma
What is respiration?
- body needs continuous supply of O2 to produce energy (ATP)
- when we use O2 to break down food to release energy or when we exercise, CO2 is produced & must be removed
Respiration definition
The taking in of O2 & removal of CO2
Respiratory system function
To transport oxygen from the air we breathe through a system of tubes into our lungs and then into the bloodstream
Structure of the lungs
-Lungs found in thorax
- protected by rib cage & separated from abdomen by diaphragm muscle
- each lung is surrounded by pleura, a double membrane which contains lubricating pleural fluid
- right lung is slightly larger than left
- right lung has 3 lobes, left has 2
Haemoglobin characteristics
-In red blood cells
- transport oxygen from lungs to tissue
- binds with oxygen to form oxyhaemoglobin
Myoglobin characteristics
-In muscle cells
- stores & releases oxygen in muscles
- high affinity for oxygen so can hold & release when levers are low
How does an oxygen molecule travel through the bloodstream?
- Air drawn through nose & mouth
- Passes through pharynx into larynx
- Epiglottis covers opening of larynx to prevent food entering lungs
- Air moves into trachea (windpipe)
- Air passes into 1 of 2 brooch - 1 enters each lung
- Air travels into bronchioles
- at the end of the bronchioles, air enters 1 of many millions of alveoli
- Gaseous exchange occurs in alveoli - takes place by diffusion
What happens when you inhale?
- External intercostal muscles contract
- diaphragm contracts (flattens)
- pulls ribcage up & out
- causes thoracic cavity size to increase
- decreased pressure in thoracic cavity
- gases move from areas of high → low pressure
-Oxygen moves from atmosphere to lungs
Exercise:
- sternocleidomaftoid muscle lifts the sternum & pectoralis minor raises s the ribs, scalene muscles (neck)
What happens when you exhale?
- external intercostal muscles relax
-Diaphragm relaxes (domes) - pulls ribcage down & in
- thoracic cavity decreases size
- thoracic cavity increases pressure
-gases move from lungs into atmosphere
Exercise:
- internal intercostals help pull ribs down
- abdominals push diaphragm up
Alveoli role
Responsible for gas exchange between lungs & blood
Alveoli structure
- dense capillary networks - supply of oxygen
- extremely thin (one cell thick) - create large surface area & small diffusion distance for greater oxygen uptake
Mechanics of breathing
- Air moves from area of high→ low pressure
- greater pressure difference = faster the air flows
- during inspiration pressure needs to be lower in lungs than atmosphere
- during expiration the pressure needs to be higher in lungs than atmosphere
Tidal volume - definition & values
Volume of air breathed in or out per breath
- rest = 0.5L
-Exercise = ↑
Inspiratory reserve volume - definition & values
Volume that can be forcibly inspired after a normal breath
-Rest = 3.1L
-Exercise =↓
Expiratory reservevolume - definition & values
Volume that can be forcibly expired after a normal breath
- rest = 1.2 L
-Exercise = slight ↓
Residual volume - definition & values
Volume that remains in the lungs after maximum expiration
-Rest =1.2L
-Exercise= no change
Vital capacity - definition & values
Volume forcibly expired after maximum inspiration in one breath
TV + IRV + ERV = VC
- rest = 4.8 L
-Exercise = slight ↓
Minute ventilation - definition & values
Volume breathed in or out per minute
-Rest =6L
-Exercise = large ↑
Total lung capacity - definition & values
Vital capacity + residual volume
-Rest =6L
-Exercise = slight ↓