6- GABA Flashcards
1
Q
Isoforms of GAD in Mammals
A
GAD 65, 67
2
Q
Baclofen
A
Selective agonist of GABA(B)R
CNS depressant
Skeletal muscle relaxant (not approved)
3
Q
Muscimol
A
GABA (A)R Agonist (orthosteric)
4
Q
Gaboxadol
A
GABA(A)R agonist
Orthosteric
5
Q
Bibulbulline
A
Potent antagonist of GABA(A)R
Binds to active site
6
Q
I/E Imbalance in Brain Disorders
A
Seizures
Autism Disorder/neurodevelopmetnal
SCZ
AD
CTE