6- GABA Flashcards

1
Q

Isoforms of GAD in Mammals

A

GAD 65, 67

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2
Q

Baclofen

A

Selective agonist of GABA(B)R

CNS depressant
Skeletal muscle relaxant (not approved)

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3
Q

Muscimol

A

GABA (A)R Agonist (orthosteric)

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4
Q

Gaboxadol

A

GABA(A)R agonist

Orthosteric

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5
Q

Bibulbulline

A

Potent antagonist of GABA(A)R

Binds to active site

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6
Q

I/E Imbalance in Brain Disorders

A

Seizures

Autism Disorder/neurodevelopmetnal

SCZ
AD
CTE

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