54. Alzheimer's Flashcards

1
Q

Most common type of dementia with 60-80% of the cases

A

alzheimer’s

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2
Q

average lifespan of someone with alzheimer’s

A

4-8 years after diagnosis and up to 20 years

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3
Q

What is considered younger onset of alzehimer’s

A

<66y

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4
Q

What happens to brain with alzheimer’s

A
  1. Nerve cell death
  2. Tissue loss
    - plaques: abn clusters of protein fragment
    - tangles: twisted strands of another protein
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5
Q

s/s alzheimers

A
  1. Memory loss that disrupts daily life
  2. Challenges in planning or solving problems.
  3. Difficulty completing familiar tasks.
  4. Confusion with time or place.
  5. Trouble understanding visual images and spatial relationships.
  6. New problems with words in speaking or writing.
  7. Misplacing things and losing the ability to retrace steps.
  8. Decreased or poor judgement.
  9. Withdrawal from work or social activities.
  10. Changes in mood and personality
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6
Q

Stages of alzehimer’s

A
  1. mild (early)
    - able to function independently
    - forgetting familiar words
    - trouble remembering names, losing everyday objects
  2. moderate (middle)
    - requires increasing care (toileting/bathing)
    - forgetfulness of personal hx
    - place/time confusion
  3. severe (later)
    - longest stage
    - requires full-time care
    - loss of awareness
    - changes in physical abilities
    - vulnerable to infections
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7
Q

Alzheimer meds:

- cholinesterase inhibitors:

A
  • prevents breakdown of ACH to keep ACH high and delays s/s
  • symptoms related to memory, thinking, language, and judgement
  • examples: donapezil (aricept)
  • galantamine (razadyne)
  • rivastigmine (exelon)
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8
Q

side effects of cholinesterase alzheimer meds

A
  • increased bowel movements
  • loss of appetite
  • N/V
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9
Q

Alzheimer meds:

- N-Methyl-D-Aspartate receptor antagonist

A
  • Regulates glutamate activity to increase information processing
  • Improves memory, attention, reason, language
  • Example: Memantine (Namenda)
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10
Q

side effects of N-Methyl-D-Aspartate alzheimer meds

A
  • constipation
  • confusion
  • dizziness
  • HA
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