510-6

Question 1

What are some cool components of saliva? 2 digestive enzymes, a digestive aid, 4 antimicrobal, and one wound healer

Answer 1

Salivary amylase & lingual lipase—mucus—lysozyme & lactoferrin & IgA & SLPI—histatin

Question 2

What are the autonomic nervous system effects on saliva?

Answer 2

Parasympathetic (Poop/Rest/Digest)-large vol of thin, serous saliva VS sympathetic(fight/flight)-small vol of thick mucus saliva

Question 3

Two types of salivary glands

Answer 3

Minor(Intrinsic)-throughout the oral mucosa Major(Extrinsic)-Large amounts of saliva with stimulation (parotid, submandibular, and sublingual) deposited to oral cavity thru ducts

Question 4

Where are minor salivary glads found in the oral cavity? What type of fluid do they secrete mostly? What are the serous glands of the vallate papillae of the tongue called (someone’s name)?

Answer 4

All of the lining and special mucosa. They mostly secrete MUCOUS aside from EBNER’s serous glands of the tongue.

Question 5

What is the result of an obstructed minor salivary gland?

Answer 5

A mucocele! Been there done that.

Question 6

What are the three (6 all together, right?!) major/extrinsic salivary glands?

Answer 6

The parotid, submandibular, & sublingual

Question 7

What types of secretetory products arise from the major salivary glands?

Answer 7

Serous(watery) Mucous(thicker, glycoproteins) and mixed.

Question 8

How much of the oral cavity saliva is produced by the parotid gland? Who got to name the parotid duct? Hint old Brophy teacher.

Answer 8

The parotid produces 25%, Stensen’s Duct.

Question 9

How much of the saliva is produced by the submandibular gland? Who got to name this one’s duct? Hint Penn Business School.

Answer 9

70% of the saliva. Wharton’s duct.

Question 10

How much saliva is produced by the sublingual gland? Who got to name the main duct? Hint: The Simpsons Who go to name the smaller ducts? Hint: think neuro-anatomy.

Answer 10

Only 5% of the saliva is produced by the sublingual gland. The major duct is Bartholin’s Duct and the minor ducts are the ducts or RIV-IN-US (not Ranvier :)

Question 11

What is Sjogren’s Syndrome?

Answer 11

SHOW-grins syndrome is an autoimmune disorder that destroys lacrimal and salivary glands resulting in dry eyes and mouth.

Question 12

Tell me the development of Calculus story…

Answer 12

Starts with the PELLICLE: thin film on tooth. Mostly glycosylated mucin and other proteins (think saliva contents too!). Then PLAQUE forms once a the Pellicle is heavily colonized by GRAM + bacteria (S. Sanguis, S. mutans, A. viscous). Once plaque becomes calcified it turns to CALCULUS.

Question 13

Thick vs thin salivary gland secretions. Name thin and its contents. Name thick and its contents.

Answer 13

Thin: Serous. Watery with enzymes, proteins. Thick: Mucous: thick, glycoproteins like mucin.

Question 14

What type of secretions do each of the major salivary glands produce?

Answer 14

Parotid:Serous Submandibular:mixed but mostly serous Sublingual: mixed but mostly Mucous.

Question 15

Where does the secretion of an acinus flow first? Intercalated duct or striated duct? What type of epithelium are these ducts?

Answer 15

Intercalated (simple cuboidal epithelium–>columnar as it approaches a striated duct) THEN striated (tall cuboidal or columnar. simple OR stratified)

Question 16

What are the three possible types of acini?

Answer 16

Serous, mucous, and mixed

Question 17

Which stains nicely? Serous or mucus?

Answer 17

Serous stains well with the eosin (water based). Mucous doesn’t stain as well so it looks lighter/FOAMY (UNLESS its a special stain).

Question 18

Compare the nuclei of a mucous cell and a serous cell.

Answer 18

Mucous-flat nucleus against the basal portion (mucous is pushing down on the nucleus) Serous-round nucleus (toward base as well)

Question 19

What type of secretion is involved in serous secretion?

Answer 19

Merocrine

Question 20

What type of cell forms the demilune?

Answer 20

Serous, thinkn mucous is thicker so it pushes out the serous cells.

Question 21

What is the role of a myoepithelial cell?

Answer 21

It is a very thin smooth muscle cell on the surface of an acini. They have been shown not to have too much influence on secretion.

Question 22

What is the difference between primary saliva and final saliva?

Answer 22

Primary:isotonic in the acinus and intercalated ducts. Final HYPOtonic as it passes thru the striated and excretory ducts.

Question 23

What types of neurotransmitters activate saliva production?

Answer 23

ACh–>muscarinic cholinergic receptors NE–>alpha and beta adrenergic receptors

Question 24

Tell me the pathway of a secretion from beginning to end.

Answer 24

serous/mucous cell–> intercalated duct–>striated duct–>excretory duct–>main excretory duct

Question 25

Which duct secretes the bicarb?

Answer 25

Striated duct

Question 26

Where is the RARE stratified columnar epithelium found in the salivary gland?

Answer 26

Excretory ducts.

Question 27

What are the two main causes of xerostomia? How is it treated?

Answer 27

Radiation therapy–really hard on the salivary glands. Show-grins syndrome(autoimmune). Treated with PILO-CAR-PINE.