510-5 Flashcards

1
Q

What type of epithelium is the epidermis?

A

Keritinized Stratified Squamous Epithelium

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2
Q

What are the four main cells of epidermis?

A

1)Keratinocytes-MOST abundant cell of the epithelium 2)Melanocytes-pigment cells in basal layer 3)Langerhans cells (dendritic cells)-from the bone marrow, present antigens to T-cells*allergic reactions! 4)Merkel’s cells (tactile cells)-in touch with sensory neurons KNOW WHAT THEY LOOK LIKE!!

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3
Q

How many layers are in thick skin and thin skin respectively?

A

Thick skin 400-600m layers thick (no hair), thin skin is ~ 75-150m thick (hair present)

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4
Q

Is epidermis vasular? innervated?

A

It is avascular and not innervated

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5
Q

Name the 5 strata of the epidermis from superficial to deep.

A

(((C-L-G-S-B))) 1)Stratum Corneum 2)Stratum Lucidum 3)Stratum Granulosum 4)Stratum Spinosum 5)Stratum Basale

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6
Q

What is the skeletal muscle of the lips?

A

Orbicularis Oris

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7
Q

What are the 4 glands of the lips?

A

1)salivary 2)mucous 3)sweat 4)sebaceous

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8
Q

What are the 3 distinct types of stratified squamous epithelia of the lips?

A

1)Thin&Hairy-Keratinized W Hair and Glands 2)Vermillion zone-Keratinized WITHOUT hair or glands 3)Oral mucosa-nonkeratinized OR parakeratinized epithelium with glands

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9
Q

What is Meissner’s Corupuscle? Where can I find one?

A

Its a nerve ending in the Vermillion zone of the lip. Makes lips perfect for kissing! and feeling things I guess.

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10
Q

What marks the junction between labial mucosa and the vermillion zone?

A

minor salivary glands! think: dry vermillion zone and wet labial mucosa

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11
Q

Since the oral mucosa is BOTH nonkeritinized and parakeratinized, what about the nuclei distinguishes parkeratinized cells?

A

The nuclei of parakeratinized cells are PYKNOTIC-dark and shrunken-nuclei.

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12
Q

What are the three layers of MUCOSA?

A

1)Stratified Squamous Epithelium 2)Lamina Propria 3)Muscularis mucosae

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13
Q

What features of the 3 mucosal layers distinguish ORAL mucosa from other mucosa?

A

EPITHELIUM:degrees of keratinization, based on type IV collagen LAMINA PROPRIA: RETE RIDGES, fibroblasts MUSCULARIS MUCOSAE:the oral mucosa has NO muscular is mucosae (we keep things moving enough with saliva!)

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14
Q

What three things can I find in the loose CT of the oral submucosa?

A

blood vessels, nerves, & minor salivary glands

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15
Q

The THREE types of ORAL CAVITY Mucosae!!!

A

Lining Mucosa, Masticatory Mucosa, Specialized

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16
Q

Where can I find Masticatory and Specialized mucosa?

A

Masticatory: Gingiva and hard palate Specialized: dorsal surface of tongue LINING is the rest! (alveolar mucosa, labial mucosa, buccal mucosa, soft palate, floor of the mouth, surface of the tongue)

17
Q

What type of epithelium is lining mucosa?

A

NONkeratinized stratified squamous epithelium

18
Q

What is the lining mucosa supported by?

A

Vascular lamina propria-FEW papillae(so its mobile!)

19
Q

Is the lining mucosa permeable?

A

Yes, think: topical anesthetic, nitroglycerin, vitamin B12, and tobacco

20
Q

What is a down growth of epithelium into the lamina propria?

A

A Rete Ridge! (interdigitated with papilla of the lamina propria)

21
Q

What are the four layers of the masticatory mucosa epithelium?

A

S. Basale-Hemidesmosomes; S. Spinosum-desmosomes; S. Granulosum-keratin granules; S. Corneum-keratinized and parakeratinized

22
Q

What are clusters of sebaceous granules in the oral mucosa? (Not all people have these..)

A

Fordyce’s granules

23
Q

What are the 5 parts of the GINGIVA?

A

1)Attached-to periosteum of the alveolar bone 2)Free-on the Crest of the alveolus 3)Gingival Margin/Crest-gingiva at the apex of the free gingiva(over the crest of the alveolus) 4)Sulcar epithelium-lines the gingival sulcus 5)Junctional Epithelium-2 basal laminae

24
Q

How does Junctional epithelium connect gingiva to tooth? WHO characterized this phenomena?

A

2 basal laminae- one to the ENAMEL (Internal Basal Lamina) and one to the connective tissue around the alveolar bone (normal Basal Lamina). Good ole Bernhard GOTTLIEB!!

25
Q

What are the two types of epithelium in the gingival sulcus?

A

1)Sulcular epithelium and 2)junctional epithelium

26
Q

How do melanocytes transfer melanin to keratinocytes? Where are melanocytes embryologically derived from?

A

Via CYTOCRINE injection. Neural Crest Cells.

27
Q

Preview: what type of oral mucosa lines the dorsal side of the tongue? Is it keratinized or nonkeratinized?

A

It is SPECIALIZED oral mucosa and it is KERATINIZED.