50. Acid Base Balance Flashcards
Introduction :-
-CO2 + H2O ——————>
When H+ increases :- acid base balance is maintained by 1. 2. 3. 1st line control :- Occurs within :- By :-
Lungs :-
Increase or decrease,,,,,,,,,by regulation of ,,,,,,,
2mpnd line control
Occurs within :-
Kidney
Last line of control
,,,,,,&,,,,,,,reabsorption or excretion
Takes :-
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PH of blood is :-
Death occurs when ph
1.
2
Changes in ph
Protein :-
Effect of acidosis on CNS :-
Effect of alkalosis on CNS :-
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Buffer :- 1st line :- Most important extra cellular buffer :- Most important intra cellular buffer :- Buffer in RBC :- Buffer action is mediated by amino acid :-
Phosphate buffer 1. 2. Ammonia buffer 1. In :- 2.
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Lungs :- 2d line control Regulate:- Only ,,,,% effective Hyperventilation :- Hypoventilation :-
Alveolar ventilation is inversely proportional to :-
So in hyperventilation :-
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Kidney Last line :- 1. Active generation of :- 2. During acidosis :- 3. During alkalosis :-
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Resorption of filtered bicarbonate ion :-
In PCT :- ,,,,% of ,,,,,,,,is ,,,,,,,,,
The excreted H+ ion reacts with :- ……is filtered and forms H2CO3 which dissociates into,,,,,,,+,,,,,
Enters :-
HCO3 produced inside ,,,,,gets ,,,,,,
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Generation of new bicarbonate ions
2 mechanism :-
1.
2.
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When Phosphate is used as buffer :-
H+ when excreted into urine
H+ connect with phosphate in URINE
Excreted
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When ammonia used in buffer
H+ excreted in urine
H+ combines with :- ammonia in urine
Excreted :-
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When phosphate and ammonia are used as buffer the acids ( ,,,,,,+,,,,,) that are excreted is known as :-
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Titratable acids :-
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Limiting PH
All the H+ ions gets buffered at the level of :-
The ph until which the H+ ions can be excreted in urine is known as :-
Limiting ph is :-
Does not reach in pct :-
The limiting ph of ,,,,,is reached at the level of ………….
Acidification of urine :-
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Acidification of urine occurs in :-
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Role of collecting duct
Acid base regulating cell in collecting duct :-
Types
1.
2.
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Acid base regulating cell in collecting duct :- Type A I cells :- Excrete :- Seen in :- Type B I cells :- Excrete :- Seen in :-
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