4. Cell Organelles And Cell Juctions Flashcards
2 important organelles of cells :-
Twin organelles :-
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Endoplasmic reticulum
2 types :-
Difference :-
15
Rough endoplasmic reticulum 3 vital functions
Ubiquitine :-
Absent ERAD result in disease :-
1.
2.
15
Smooth Endoplasmic Reticulum :- 3 vital functions 1. 2. 3. Express :-
16
Golgi apparatus
Major function :-
1. ( glycosalation )
2. ( mannose 6 phosphate )
16
Parts of Golgi apparatus :-
1.
2.
3.
16
Lysosomes Destruction of :- Which channel is present in lysosomes :- Also destroy Also called :- Enzyme in lysosomes :-
17
Autophagy
Helps in
Starvation :-
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Peroxisome function :-
1.
2.
Pseudocatalase
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Cytoskeleton filaments :- Classification 1. 2. 3.
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Microtubles 3 proteins 1. 2. 3. 3 functions 1. 2. 3.
Kinesin does :-
Dynein does :-
Also mechanism of transport in :-
Absent dynenin :-
Triad :-
May be also present with :-
Tubilin :-
18-19
Micro tubule inhibitors :- MOA Use Example :- 1. 2.
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Microfilament s Example 1. 2. 2 vital fuction 1. 2.
Listeria monocytogenes :-
19
Intermediate filaments Most :- Considered as :- Examples 1. 2. 3. 4. 5.
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Keratin
:-
Tumor marker :-
19
Desmin
Tumor marker in :-
19
Vimentin
Tumor marker in :-
GFAP
Present in :-
Mum or marker for :-
Lamin
Present in
Mutation in lamin :-
20
Markers of cellular components
- Nucleus
a.
b. - Mitochondrion:-
- Endoplasmic reticulum :-
- Golgi apparatus :-
- Lysosomes :-
- Peroxisomes :-
- Cytoplasm :-
- Cell membrane :-
20
Cellular juction
Types
1.
2.
20
Cell to cell junctions 1. 2. 3. 4.
20
Cell to basement membrane 1. 2. a. b. c.
20
Cellular junctions
1. Zone Adherence :- attached to :-
2. Desmosomes :- attached to :- seen :-
3. Tight junction :- aka :- formed by protein :- location
:- function
4. Gap juction :- present in :- formed by protein :-
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