43. GLomerular Filteration Rate

Question 1

Fuctional unit of kidney :-
No nephron per kidney :-
Unique feature:-
Filteration size :-

Answer 1

213

Question 2

Reasons proteins are not filtered :-
1.
2.
3.

Answer 2

213

Question 3

Slit diaphragm integrity:-
1.
2.
3 .

Answer 3

213

Question 4

Favouring force :-
???????
=

Answer 4

213

Question 5

Opposing force 
1. 
=
2. 
=

Answer 5

213

Question 6

Net filteration pressure =

Answer 6

214

Question 7

Afferent arteriolar constriction

1. Caused by
   a.
   b.
2. Effect on GFR :-
3. Effect on RBF

Answer 7

214

Question 8

Afferent arteriolar relaxation :-

1. Caused by
   a.
2. Effect on GFR :-
3. Effect on RBF :-

Answer 8

214

Question 9

Efferent arteriolar constriction

1. Caused by
   a.
2. Effect on GFR :-
3. Effect on RBF

Answer 9

214

Question 10

Efferent arteriolar relaxation

1. Caused by
   a.
2. Effect on GFR :-
3. Effect on RBF

Answer 10

214

Question 11

Measurement of GFR
Gold standard substance for measurement of GFR is :-
Criteria for inulin :-

Formula for GFR :-

Normal inulin clearance :-
GFR :-

Gold standard method to measure GFR :-
But MC used method :-
New marker for estimation of GFR :-

Answer 11

214

Question 12

Importance of measurement of GFR :-

Normal renal blood flow :-
Renal plasma flow =

Substance used estimate renal plasma flow :-
Estimated RPF =
Actual RPF =

Answer 12

215

Question 13

Filteration Fraction =

Answer 13

215

Question 14

Regulation of GFR :-
1. Auto regulation of GFR :-
Change in BP between ,,,,,,,to,,,,,,,,mmhg
GFR remains constant

Mechanism of Autoregulation

Myogenic auto regulation:- due to

Tubuloglomerular feedback:- due to

Answer 14

215

Question 15

Mesangial cells

Mesangial cells contraction :- 
Leads to :- 
Caused by 
1. 
2. 
3.

Answer 15

216

Question 16

Mesangial cells relaxation :- 
Leads to :- 
Caused by 
1. 
2. 
3.

Answer 16

216