5 systematic reviews of RCT's

Question 1

What 3 factors contribute to is evidence based medicine

Answer 1

individual clinical expertise

best external evidence

patient values and expectations

Question 2

What is publication bias?

Answer 2

when the publication of research results depends on their nature and direction

Question 3

What is positive results bias?

Answer 3

authors more likely to submit or editors accept, positive than negative or inconclusive results

Question 4

What is outcome reporting bias?

Answer 4

when several outcomes within a trial are measured but are reported selectively depending on the strength and direction of those results

Question 5

What are the benefits of using reviews?

Answer 5

smaller volume of literature
new information accesssible
some reviews are extremely good and have taken considerable time to find relevant information

Question 6

What is a systematic review?

Answer 6

the research method used to synthesise multiple pieces of research evidence on the effectiveness of a treatment

Question 7

What are the 8 stages to a systematic review?

Answer 7

define question
write protocol
search for evidence
select relevant studies
appraise studies
extract, analyse, and summarise data 
interpret review results
discussion and conclusions

Question 8

What is the difference between a systematic review and a narrative review?

Answer 8

narrrative - general discussion, no explicit hypothesis, kinda shit

Question 9

What is a meta-analysis?

Answer 9

statistical techniques are used to combine the quantitative results from a number of studies

Question 10

What are the 3 parts to a critical appraisal?

Answer 10

trustworthy/valid?
results?
useful?

Question 11

How might you see if a systematic review asks a clearly focused question?

Answer 11

PICO