20 ageing Flashcards
What are the types of aging?
primary - natural decline
secondary - results from disease
Who documented the cognitive and social changes through life?
cognitive - piaget
social - erikson
What causes the onset on menopause?
estrogen - instability in thermo-regulation
What are the primary and secondary symptoms of menopause?
primary - hot flushes and night sweats
secondary - vaginal dryness, depression, fatigue
Name 4 ways which cellular ageing occurs
1 - Hayflick limit
2 - cross linking
3 - free radicals
4 - DNA
What is the hayflick limit?
limit to number of times a cell can divide - decreases as we age
How does cross linking affect ageing?
proteins in cells produce molecules, making the body stiffer
what happens to the brain as we age?
cell body and axon has neurofibrillary tangles
dendrites frazle away, neurone is less sensitive
plaques
What happens to the cardiovascular system with age?
fat deposits
stiffening of artery walls
What happens to the ventilatory system with age?
rib cage and air passages stiffen
What disease is associated with neurofibrilatory tangles?
Alzheimer’s
What microscopic changes occur in dementia?
neurofibrilary tangles
neuritic plates
