5: Synaptic Transmission Flashcards
1
Q
List the events at a chemical synapse
A
7 steps
look through slides
2
Q
What are the key features of a chemical synapse
A
- Vesicles containing neurotransmitter (synthesis and transport to terminal)
- Docking apparatus for the vesicles (and recycling)
- Voltage gated Ca2+ channels
- Synaptic cleft (recycling of transmitter)
- Post synaptic receptors
3
Q
What is a common example of a chemical synapse
A
Botox
- Botulinum toxin -prevents vesicle fusion and blocks the synapse
4
Q
What is spatial summation
A
Post synaptic potentials from different locations overlap
spatial –> space –> location
5
Q
What is temporal summation
A
Post-synaptic potentials overlap in time
temporal –> time
6
Q
What are some other mechanisms of synaptic modulation? (3)
A
- Faciliation
- Post-tetanic potentiation
- Fatigue
