4: Action potentials Flashcards

1
Q

Describe the relationship between the permeability of the membrane to the conductance/action potential

A

The more permeable the membrane to a particular ion, the greater the conductance of the membrane to that ion

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2
Q

What are transmembrane domains?

A

Protein of the voltage gated Na+ channel has 4 subunits which are already connected. The parts in the subunit are called the transmembrane domain

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3
Q

What type of channel are Na+

A

Voltage gated

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4
Q

What are the three sections of voltage gated Na+ channels

A
  1. Voltage sensor -ON
  2. Selectivity filter
  3. Inactivation gate -OFF
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5
Q

Describe how the inactivation gate works

A

“ball and chain model”

- Look through lecture slides

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6
Q

What drug are voltage gated Na+ channels blocked by?

A

Tetrodotoxin

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7
Q

What are voltage gated K+ channels blocked b

A

tetrathylammonium

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8
Q

Describe the action/movement of action potentials

A

slides

  • Stimulus-gated Na+ channels open
  • Voltage-gated Na+ channels open
  • Voltage-gated Na+ channels close
  • Voltage-gated K+ channels open
  • Voltage-gated K+ channels close
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9
Q

Describe the absolute refractory period

A

slides

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10
Q

Describe the relative refractatory period

A

slides

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11
Q

List methods to improve action potential conduction velocity

A
  • Increase axon diameter -decrease r(in)
  • Increase axon insulation -increase m
  • Saltatory conduction between nodes of Ranvier
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