5 - AROMATICS (QUINONES)

Question 1

what is the bombardier beetle reaction?

Answer 1

water, oxygen, benzoquinone and heat
up to 100°C
boiling foul smelling liquid is expelled with a loud popping sound by the bombardier beetle
in its secretion glands the beetle mixes hydroquinone and hydrogen peroxide
the enzymes are catalase/peroxidase

Question 2

how is hydrogen peroxide industrially synthesized?

Answer 2

Question 3

know about phenoxy radical coupling

Question 4

what are building blocks of lignins?

Answer 4

Question 5

what is galanthamine used for and why is this synthesis special?

Answer 5

used for the treatment of mild to moderate alzheimer’s
this molecule has 3 chiral centers, so there are 8 possible isomers
you have to use chiral catalysts to do asymmetrical synthesis

Question 6

which agent can be used to make a phenoxy radical?

Answer 6

K3Fe(CN)6

Question 7

what is the structure of galantamine?

Answer 7

Question 8

galantamine synthesis mechanism

Answer 8